{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["21(12)"],"submitter":["EFSA Panel on Food Additives and Flavourings (FAF)"],"pubmed_abstract":["This opinion addresses the re-evaluation of erythritol (E 968) as food additive and an application for its exemption from the laxative warning label requirement as established under Regulation (EU) No 1169/2011. Erythritol is a polyol obtained by fermentation with <i>Moniliella pollinis</i> BC or <i>Moniliella megachiliensis</i> KW3-6, followed by purifications and drying. Erythritol is readily and dose-dependently absorbed in humans and can be metabolised to erythronate to a small extent. Erythritol is then excreted unchanged in the urine. It does not raise concerns regarding genotoxicity. The dataset evaluated consisted of human interventional studies. The Panel considered that erythritol has the potential to cause diarrhoea in humans, which was considered adverse because its potential a"],"journal":["EFSA journal. European Food Safety Authority"],"pagination":["e8430"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10731997"],"repository":["biostudies-literature"],"pubmed_title":["Re-evaluation of erythritol (E 968) as a food additive."],"pmcid":["PMC10731997"],"pubmed_authors":["Bruzell E","Mortensen A","Aquilina G","Tard A","Wallace H","Gurtler R","Ntzani E","Chipman J","Barmaz S","Shah R","Wright M","Passamonti S","Batke M","Halldorsson T","Boon P","Smeraldi C","Manco M","Lindtner O","EFSA Panel on Food Additives and Flavourings (FAF)","Engel KH","Frutos Fernandez MJ","Laganaro M","Mennes W","FitzGerald R","Waalkens-Berendsen I","Fowler PJ","Furst P","Degen G","Younes M","Crebelli R","Civitella C","Gundert-Remy U","D'Angelo L","Rincon AM","Husoy T","Lodi F","Castle L","Moldeus P","LeBlanc JC","Fortes C"],"additional_accession":[]},"is_claimable":false,"name":"Re-evaluation of erythritol (E 968) as a food additive.","description":"This opinion addresses the re-evaluation of erythritol (E 968) as food additive and an application for its exemption from the laxative warning label requirement as established under Regulation (EU) No 1169/2011. Erythritol is a polyol obtained by fermentation with <i>Moniliella pollinis</i> BC or <i>Moniliella megachiliensis</i> KW3-6, followed by purifications and drying. Erythritol is readily and dose-dependently absorbed in humans and can be metabolised to erythronate to a small extent. Erythritol is then excreted unchanged in the urine. It does not raise concerns regarding genotoxicity. The dataset evaluated consisted of human interventional studies. The Panel considered that erythritol has the potential to cause diarrhoea in humans, which was considered adverse because its potential a","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Dec","modification":"2026-06-22T03:17:55.515Z","creation":"2025-04-04T10:30:22.14Z"},"accession":"S-EPMC10731997","cross_references":{"pubmed":["38125972"],"doi":["10.2903/j.efsa.2023.8430"]}}