biostudies-literatureOertli JMSwiss National Science FoundationWellcome Trust18https://www.ebi.ac.uk/biostudies/studies/S-EPMC10732091biostudies-literatureUnknown12(12)<h4>Purpose</h4>The purpose of this study was to establish and validate a novel fundus-controlled dark-adaptometry method.<h4>Methods</h4>We developed a custom dark-adaptometry software for the S-MAIA device using the open-perimetry-interface. In the validation-substudy, participants underwent dark-adaptometry testing with a comparator device (MonCvONE, 59% rhodopsin bleach, cyan and red stimuli centered at 2 degrees, 4 degrees, and 6 degrees eccentricity). Following a brief break (approximately 5 minutes), the participants were bleached again and underwent dark-adaptometry testing with the S-MAIA device (same loci). In the retest reliability-substudy, participants were tested twice with the S-MAIA device (same loci as above). Nonlinear curve fitting was applied to extract dark-adaptation Translational vision science & technologyEstablishing Fully-Automated Fundus-Controlled Dark Adaptometry: A Validation and Retest-Reliability Study.PMC10732091201165310030Oertli JMJeffrey BGPfau MPfau KScholl HPNfalseEstablishing Fully-Automated Fundus-Controlled Dark Adaptometry: A Validation and Retest-Reliability Study.<h4>Purpose</h4>The purpose of this study was to establish and validate a novel fundus-controlled dark-adaptometry method.<h4>Methods</h4>We developed a custom dark-adaptometry software for the S-MAIA device using the open-perimetry-interface. In the validation-substudy, participants underwent dark-adaptometry testing with a comparator device (MonCvONE, 59% rhodopsin bleach, cyan and red stimuli centered at 2 degrees, 4 degrees, and 6 degrees eccentricity). Following a brief break (approximately 5 minutes), the participants were bleached again and underwent dark-adaptometry testing with the S-MAIA device (same loci). In the retest reliability-substudy, participants were tested twice with the S-MAIA device (same loci as above). Nonlinear curve fitting was applied to extract dark-adaptation 2023-01-01T00:00:00Z2023 Dec2026-05-28T19:11:47.962Z2025-04-05T20:12:24.762ZS-EPMC107320913811249610.1167/tvst.12.12.18