biostudies-literatureRichard SAHenry M. Jackson FoundationNational Institute of Allergy and Infectious DiseaseNIAID NIH HHSInfectious Disease Clinical Research ProgramDefense Health ProgramNational Institutes of HealthDepartment of DefenseUniformed Services University of the Health Sciencesofad579https://www.ebi.ac.uk/biostudies/studies/S-EPMC10733205biostudies-literatureUnknown10(12)<h4>Background</h4>The long-term effects of coronavirus disease 2019 (COVID-19) on physical fitness are unclear, and the impact of vaccination on that relationship is uncertain.<h4>Methods</h4>We compared survey responses in a 1-year study of US military service members with (n = 1923) and without (n = 1591) a history of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We fit Poisson regression models to estimate the association between history of SARS-CoV-2 infection and fitness impairment, adjusting for time since infection, demographics, and baseline health.<h4>Results</h4>The participants in this analysis were primarily young adults aged 18-39 years (75%), and 71.5% were male. Participants with a history of SARS-CoV-2 infection were more likely to report difficulOpen forum infectious diseasesDecreased Self-reported Physical Fitness Following SARS-CoV-2 Infection and the Impact of Vaccine Boosters in a Cohort Study.PMC10733205HU00012020067Y1-AI-5072HU00011920111Y01 AI005072Tribble DREdwards MSRozman JSTurner LNElnahas NMohammed RBazan SEWest CTso MLanteri LCSamuels EFlanagan RLindholm MDClark DAustin ALucas CChao TTSanchez MRutt ALalani TTribble DLindholm DARichard SASmith LAMartin MOdineal CDTimlin MMFox CRichard SSandoval PConlon CCMaldonado CMehrer JMarkelz LAColombo REBaya AJones MMWood MSBanks SMacias ELarson DTO'Connell RJPollett SMadar CJones MUReterstoff KSimons CMM HLarson LDRozman JDavies JLove PKSilva AColombo RByrne CBazan LSHogan VStarr CHarrington CMody RMKim LLivezey LJSmith AGEverson CKStein MEPICC COVID-19 Cohort Study GroupEpsi NParmelee EMorris MJLee LTDeLeon SMejia JCammarata SAgan BKChi SFuentes AWellington CTLibraty DSainato MREwers ECFaestel CPTant RGanesan AMiyasato KSwitzer MMChung KResendez RUyehara CUlomi LEnglish CLanter KEwers MEAdams HHostler LJCowden CJT AGrogan LSSimons MPOlsen CHostler LDBradley CNwachukwu PDimascio-Johnson NJennings DWarkentien CTBowman JCarpenter RHockenbury NMorales CBerjohn CMGordon MLRobb-McGrath WAgan BSaunders DReynolds KHuprikar MNDarling LMBerjohn CCTelu KSaunders CDMount CCChristian MJarral UMeyer JHickey CPMaldonado CJMontes JPerreault LMHuntsberger SKirkland NFlanagan LRRusiecki JKronmann CKFries ALivezey JFritschlanski MPurves SScher AIGlinn CHuprikar NRodriguez JLaing ESkinner CCChapleau RBarton BIskander CJColombo CJBurgess CTMaves RBarahona IBurgess THMalloy AJohnson BMerritt TMerritt SLago MKSchofield CSnow AMusfeldt LDHadley AColombo LCUtz GHunter MTPeel SAndronescu LWayman MLeslie NKamara CIMende KR CChenoweth JChambers SLis CSSmith RMaves RCScher AMody RFerguson CTPollett SDBroder CGallagher LKFries ACBlair PfalseDecreased Self-reported Physical Fitness Following SARS-CoV-2 Infection and the Impact of Vaccine Boosters in a Cohort Study.<h4>Background</h4>The long-term effects of coronavirus disease 2019 (COVID-19) on physical fitness are unclear, and the impact of vaccination on that relationship is uncertain.<h4>Methods</h4>We compared survey responses in a 1-year study of US military service members with (n = 1923) and without (n = 1591) a history of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We fit Poisson regression models to estimate the association between history of SARS-CoV-2 infection and fitness impairment, adjusting for time since infection, demographics, and baseline health.<h4>Results</h4>The participants in this analysis were primarily young adults aged 18-39 years (75%), and 71.5% were male. Participants with a history of SARS-CoV-2 infection were more likely to report difficul2023-01-01T00:00:00Z2023 Dec2026-06-03T09:52:10.113Z2025-04-05T15:54:02.58ZS-EPMC107332053813059610.1093/ofid/ofad579