biostudies-literatureJackson AMBritish Heart FoundationBHF Clinical Research Training FellowshipBHF Centre of Research ExcellenceVera Melrose Heart Failure Research Fund5128-5141https://www.ebi.ac.uk/biostudies/studies/S-EPMC10733720biostudies-literatureUnknown44(48)<h4>Background and aims</h4>The epidemiology of peripartum cardiomyopathy (PPCM) in Europe is poorly understood and data on long-term outcomes are lacking. A retrospective, observational, population-level study of validated cases of PPCM in Scotland from 1998 to 2017 was conducted.<h4>Methods</h4>Women hospitalized with presumed de novo left ventricular systolic dysfunction around the time of pregnancy and no clear alternative cause were included. Each case was matched to 10 controls. Incidence and risk factors were identified. Morbidity and mortality were examined in mothers and children.<h4>Results</h4>The incidence of PPCM was 1 in 4950 deliveries. Among 225 women with PPCM, obesity, gestational hypertensive disorders, and multi-gestation were found to be associated with having the condEuropean heart journalA 20-year population study of peripartum cardiomyopathy.PMC10733720FS/18/14/33330RE/18/6/34217McMurray JJVMacartney MBrooksbank KLennie VJapp AWeir RANeary PPetrie MCBrown CFrancis MVickers DJhund PSDawson DJackson AMLeslie SJMartin TVenkatasubramanian SfalseA 20-year population study of peripartum cardiomyopathy.<h4>Background and aims</h4>The epidemiology of peripartum cardiomyopathy (PPCM) in Europe is poorly understood and data on long-term outcomes are lacking. A retrospective, observational, population-level study of validated cases of PPCM in Scotland from 1998 to 2017 was conducted.<h4>Methods</h4>Women hospitalized with presumed de novo left ventricular systolic dysfunction around the time of pregnancy and no clear alternative cause were included. Each case was matched to 10 controls. Incidence and risk factors were identified. Morbidity and mortality were examined in mothers and children.<h4>Results</h4>The incidence of PPCM was 1 in 4950 deliveries. Among 225 women with PPCM, obesity, gestational hypertensive disorders, and multi-gestation were found to be associated with having the cond2023-01-01T00:00:00Z2023 Dec2025-04-26T07:46:35.782Z2025-04-06T12:29:16.858ZS-EPMC107337203780423410.1093/eurheartj/ehad626