{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9(12)"],"submitter":["Qin P"],"pubmed_abstract":["The Gram-negative bacterium <i>Pseudomonas plecoglossicida</i> has caused visceral granulomas disease in several farmed fish species, including large yellow croaker (<i>Larimichthys crocea</i>), which results in severe economic losses. Type III secretion systems (T3SS) are protein secretion and translocation nanomachines widely employed by many Gram-negative bacterial pathogens for infection and pathogenicity. However, the exact role of T3SS in the pathogenesis of <i>P. plecoglossicida</i> infection is still unclear. In this study, a T3SS translocators deletion strain (△<i>popBD</i>) of <i>P. plecoglossicida</i> was constructed to investigate the function of T3SS. Then comparative secretome analysis of the <i>P. plecoglossicida</i> wild-type (WT) and △<i>popBD</i> mutant strains was conduc"],"journal":["Heliyon"],"pagination":["e22669"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10746435"],"repository":["biostudies-literature"],"pubmed_title":["Comparative secretome analysis reveals cross-talk between type III secretion system and flagella assembly in <i>Pseudomonas plecoglossicida</i>."],"pmcid":["PMC10746435"],"pubmed_authors":["Qin P","Luan Y","Yang J","Li Y","Shao G","Munang'andu HM","Chen X","Wu T"],"additional_accession":[]},"is_claimable":false,"name":"Comparative secretome analysis reveals cross-talk between type III secretion system and flagella assembly in <i>Pseudomonas plecoglossicida</i>.","description":"The Gram-negative bacterium <i>Pseudomonas plecoglossicida</i> has caused visceral granulomas disease in several farmed fish species, including large yellow croaker (<i>Larimichthys crocea</i>), which results in severe economic losses. Type III secretion systems (T3SS) are protein secretion and translocation nanomachines widely employed by many Gram-negative bacterial pathogens for infection and pathogenicity. However, the exact role of T3SS in the pathogenesis of <i>P. plecoglossicida</i> infection is still unclear. In this study, a T3SS translocators deletion strain (△<i>popBD</i>) of <i>P. plecoglossicida</i> was constructed to investigate the function of T3SS. Then comparative secretome analysis of the <i>P. plecoglossicida</i> wild-type (WT) and △<i>popBD</i> mutant strains was conduc","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Dec","modification":"2026-04-08T15:20:14.42Z","creation":"2025-02-19T01:46:06.375Z"},"accession":"S-EPMC10746435","cross_references":{"pubmed":["38144336"],"doi":["10.1016/j.heliyon.2023.e22669"]}}