{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["4(1)"],"submitter":["Rueb M"],"pubmed_abstract":["The majority of traumatic encephalopathy syndrome (TES) cases have been reported in former contact sport athletes. This is the first case with TES in a 19-year-old male patient with progressive cognitive decline after daily domestic physical violence through repeated hits to the head for 15 years. The patient presented with a moderate depressive episode and progressive cognitive decline. Tau positron emission tomography (PET) with 220 MBq of [<sup>18</sup>F]PI-2620 revealed increased focal signal at the frontal and parietal white/gray matter border. Brain magnetic resonance imaging (MRI) showed a cavum septum pellucidum, reduced left-sided hippocampal volume, and a left midbrain lesion. Cerebrospinal fluid results showed elevated total and p-tau. Neurocognitive testing at admission showed "],"journal":["Neurotrauma reports"],"pagination":["857-862"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10754342"],"repository":["biostudies-literature"],"pubmed_title":["Traumatic Encephalopathy Syndrome and Tauopathy in a 19-Year-Old With Child Abuse."],"pmcid":["PMC10754342"],"pubmed_authors":["Rueb M","Gersing A","Simren J","Adorjan K","Brendel M","Zetterberg H","Koerte IK","Rauen K"],"additional_accession":[]},"is_claimable":false,"name":"Traumatic Encephalopathy Syndrome and Tauopathy in a 19-Year-Old With Child Abuse.","description":"The majority of traumatic encephalopathy syndrome (TES) cases have been reported in former contact sport athletes. This is the first case with TES in a 19-year-old male patient with progressive cognitive decline after daily domestic physical violence through repeated hits to the head for 15 years. The patient presented with a moderate depressive episode and progressive cognitive decline. Tau positron emission tomography (PET) with 220 MBq of [<sup>18</sup>F]PI-2620 revealed increased focal signal at the frontal and parietal white/gray matter border. Brain magnetic resonance imaging (MRI) showed a cavum septum pellucidum, reduced left-sided hippocampal volume, and a left midbrain lesion. Cerebrospinal fluid results showed elevated total and p-tau. Neurocognitive testing at admission showed ","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023","modification":"2025-04-19T14:30:34.024Z","creation":"2025-04-19T14:30:34.024Z"},"accession":"S-EPMC10754342","cross_references":{"pubmed":["38156074"],"doi":["10.1089/neur.2023.0078"]}}