{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["14(1)"],"submitter":["Deja E"],"pubmed_abstract":["<h4>Objectives</h4>The Bronchiolitis Endotracheal Surfactant Study (BESS) is a randomised controlled trial to determine the efficacy of endo-tracheal surfactant therapy for critically ill infants with bronchiolitis. To explore acceptability of BESS, including approach to consent within a limited time frame, we explored parent and staff experiences of trial involvement in the first two bronchiolitis seasons to inform subsequent trial conduct.<h4>Design</h4>A mixed-method embedded study involving a site staff survey, questionnaires and interviews with parents approached about BESS.<h4>Setting</h4>Fourteen UK paediatric intensive care units.<h4>Participants</h4>Of the 179 parents of children approached to take part in BESS, 75 parents (of 69 children) took part in the embedded study. Of these"],"journal":["BMJ open"],"pagination":["e077023"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10773389"],"repository":["biostudies-literature"],"pubmed_title":["Stakeholders' perspectives on clinical trial acceptability and approach to consent within a limited timeframe: a mixed methods study."],"pmcid":["PMC10773389"],"pubmed_authors":["Osman A","Ali AM","Woolfall K","Mogan S","Sundararajan S","Playfor SD","McNamara PS","Armstrong D","Plaatjies N","Coles S","Beadon K","Thorn N","Patel R","Jennings CF","Scriven E","Davies PE","Cunningham S","Paulson S","Minchin H","Riley EK","Postle A","Ronan C","McCormick J","Richardson J","Parslow R","Peak M","Fox S","Mackerness C","Pond J","Cook A","Stiven J","Owen S","Parkin H","Lyons J","Postlethwaite C","Browne W","Mellish C","Preston J","Best A","Summers C","Panchal M","Lo TY","Griksaitis M","Morgan DJ","Madsen J","Reed S","Jones A","Jones D","Rad L","Terris M","Clark HW","Turner M","Mander M","Crate L","Ritson PC","Dawson A","Reeves K","Semple MG","Price L","Siddiqi S","BESS Investigators","Milner P","Marley H","Linton V","Wood A","Allen E","McCorkell J","Tooke C","Clarke H","Miert CV","Sarfatti A","Linton C","Curtis T","Deja E","Roberts N","Weitz J","Pappachan J","Kanaris C","Claydon R","Thompson C","Thorburn K","Baptiste K","Murray T","Winmill H","Clarke S","Barker C","Kumar R","Jirasek P","Knott C","Fowler C","Child H","Kirupananthan R","Morris KP","Milburn N","Nugent O","Sinfield F","McMinnis R","Nelson C","Brincat E","Bunni LT","Parker H","Callaghan H","Lampariello S","Ramaiah RN","Caruana L","Compton V","Davis PJ","Schadenberg A","O'Malley L","Lamb C","Marscheider R","McClelland N","Moitt T","Cipriano B","Eames SJ","Stancombe A","Etherington N","Alexander J","Tomlinson J","Ramesh P","Williamson G","Alexander C","Agbeko R","Williamson P","Khalid N","Marshall R","Teeley K","Gavin BC","Osaghae B","Oliver Z","Gates S","Rimmer L","Payne H","Levin R","Donohue C","Simons C"],"additional_accession":[]},"is_claimable":false,"name":"Stakeholders' perspectives on clinical trial acceptability and approach to consent within a limited timeframe: a mixed methods study.","description":"<h4>Objectives</h4>The Bronchiolitis Endotracheal Surfactant Study (BESS) is a randomised controlled trial to determine the efficacy of endo-tracheal surfactant therapy for critically ill infants with bronchiolitis. To explore acceptability of BESS, including approach to consent within a limited time frame, we explored parent and staff experiences of trial involvement in the first two bronchiolitis seasons to inform subsequent trial conduct.<h4>Design</h4>A mixed-method embedded study involving a site staff survey, questionnaires and interviews with parents approached about BESS.<h4>Setting</h4>Fourteen UK paediatric intensive care units.<h4>Participants</h4>Of the 179 parents of children approached to take part in BESS, 75 parents (of 69 children) took part in the embedded study. Of these","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Jan","modification":"2025-04-03T21:31:07.55Z","creation":"2025-04-03T21:31:07.55Z"},"accession":"S-EPMC10773389","cross_references":{"pubmed":["38167280"],"doi":["10.1136/bmjopen-2023-077023"]}}