{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12(12)"],"submitter":["Jiang Z"],"pubmed_abstract":["Traditional intensity-modulated radiation therapy (IMRT) planning for cervical cancer is time-consuming and require iterative repeated optimization. In this study, we focused on leveraging multi-criteria optimization (MCO) to reduce the impact of small bowel high-dose indices on other optimization targets, thereby providing a rapid approach to individualized IMRT for cervical cancer patients. Our research involved a cohort of 25 cervical cancer patients who underwent IMRT radiotherapy. The patient inclusion criteria were as follows: (I) histopathological confirmation of cervical cancer, (II) underwent IMRT radiation therapy, and (III) a prescribed dose of 180 cGy/28 fractions for the patient. All plans were replanned by an experienced dosimetrist without the MCO (W-IMRT). On the basis of t"],"journal":["Translational cancer research"],"pagination":["3255-3265"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10774067"],"repository":["biostudies-literature"],"pubmed_title":["Advantages of IMRT optimization with MCO compared to IMRT optimization without MCO in reducing small bowel high dose index for cervical cancer patients-individualized treatment options."],"pmcid":["PMC10774067"],"pubmed_authors":["Zhang G","Yin Y","Jiang Z","Zhang X","Sun T","Kong X"],"additional_accession":[]},"is_claimable":false,"name":"Advantages of IMRT optimization with MCO compared to IMRT optimization without MCO in reducing small bowel high dose index for cervical cancer patients-individualized treatment options.","description":"Traditional intensity-modulated radiation therapy (IMRT) planning for cervical cancer is time-consuming and require iterative repeated optimization. In this study, we focused on leveraging multi-criteria optimization (MCO) to reduce the impact of small bowel high-dose indices on other optimization targets, thereby providing a rapid approach to individualized IMRT for cervical cancer patients. Our research involved a cohort of 25 cervical cancer patients who underwent IMRT radiotherapy. The patient inclusion criteria were as follows: (I) histopathological confirmation of cervical cancer, (II) underwent IMRT radiation therapy, and (III) a prescribed dose of 180 cGy/28 fractions for the patient. All plans were replanned by an experienced dosimetrist without the MCO (W-IMRT). On the basis of t","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Dec","modification":"2025-04-22T18:13:10.054Z","creation":"2025-04-06T02:21:25.271Z"},"accession":"S-EPMC10774067","cross_references":{"pubmed":["38197072"],"doi":["10.21037/tcr-22-2792"]}}