biostudies-literatureFu NZaikang TongZhejiang Science and Technology Major Program on Agricultural New Variety BreedingJunhong ZhangNational Natural Science Foundation of China545https://www.ebi.ac.uk/biostudies/studies/S-EPMC10778748biostudies-literatureUnknown25(1)Calmodulin (CaM) and calmodulin-like (CML) proteins are major Ca²⁺ sensors involved in the regulation of plant development and stress responses by converting Ca²⁺ signals into appropriate cellular responses. However, characterization and expression analyses of <i>CaM</i>/<i>CML</i> genes in the precious species, <i>Phoebe bournei</i>, remain limited. In this study, five <i>PbCaM</i> and sixty <i>PbCML</i> genes were identified that only had EF-hand motifs with no other functional domains. The phylogenetic tree was clustered into 11 subgroups, including a unique clade of <i>PbCaM</i>s. The <i>PbCaM</i>s were intron-rich with four EF-hand motifs, whereas <i>PbCML</i>s had two to four EF-hands and were mostly intronless. <i>PbCaM</i>s/<i>CML</i>s were unevenly distributeInternational journal of molecular sciencesGenome-Wide Identification and Expression Analysis of Calmodulin and Calmodulin-like Genes, Revealing <i>CaM3</i> and <i>CML13</i> Participating in Drought Stress in <i>Phoebe bournei</i>.PMC10778748Grant No. 2021C02070-102021C02070-10Grant No. 3217182832171828Zhang JZhang YTong ZHan XYang QFu NWang LfalseGenome-Wide Identification and Expression Analysis of Calmodulin and Calmodulin-like Genes, Revealing <i>CaM3</i> and <i>CML13</i> Participating in Drought Stress in <i>Phoebe bournei</i>.Calmodulin (CaM) and calmodulin-like (CML) proteins are major Ca²⁺ sensors involved in the regulation of plant development and stress responses by converting Ca²⁺ signals into appropriate cellular responses. However, characterization and expression analyses of <i>CaM</i>/<i>CML</i> genes in the precious species, <i>Phoebe bournei</i>, remain limited. In this study, five <i>PbCaM</i> and sixty <i>PbCML</i> genes were identified that only had EF-hand motifs with no other functional domains. The phylogenetic tree was clustered into 11 subgroups, including a unique clade of <i>PbCaM</i>s. The <i>PbCaM</i>s were intron-rich with four EF-hand motifs, whereas <i>PbCML</i>s had two to four EF-hands and were mostly intronless. <i>PbCaM</i>s/<i>CML</i>s were unevenly distribute2023-01-01T00:00:00Z2023 Dec2026-05-26T20:02:24.004Z2024-11-09T13:36:54.889ZS-EPMC107787483820371510.3390/ijms25010545