biostudies-literatureRamachandran PVHerbert C. Brown Center for Borane Research268https://www.ebi.ac.uk/biostudies/studies/S-EPMC10780903biostudies-literatureUnknown29(1)Borane-pyridine acts as an efficient (5 mol%) liquid catalyst, providing improved solubility for the direct amidation of a wide range of aromatic and aliphatic carboxylic acids and amines to form secondary and tertiary carboxamides. Tolerance of potentially incompatible halo, nitro, and alkene functionalities has been demonstrated.Molecules (Basel, Switzerland)Borane-Pyridine: An Efficient Catalyst for Direct Amidation.PMC10780903N/ARamachandran PVSingh AHamann HJWalker HfalseBorane-Pyridine: An Efficient Catalyst for Direct Amidation.Borane-pyridine acts as an efficient (5 mol%) liquid catalyst, providing improved solubility for the direct amidation of a wide range of aromatic and aliphatic carboxylic acids and amines to form secondary and tertiary carboxamides. Tolerance of potentially incompatible halo, nitro, and alkene functionalities has been demonstrated.2024-01-01T00:00:00Z2024 Jan2025-04-22T10:37:58.44Z2025-04-05T23:39:10.477ZS-EPMC107809033820284910.3390/molecules29010268