{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhang D"],"funding":["Projects of Science and Technology Department of Sichuan Province","The National 973 Project","Science and Technology Department of Chengdu City","National Natural Science Foundation of China","Japan Society for the Promotion of Science"],"pagination":["e13397"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10799210"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["25(1)"],"pubmed_abstract":["Rhizoctonia solani AG-1 IA causes a necrotrophic rice disease and is a serious threat to rice production. To date, only a few effectors have been characterized in AG-1 IA. We previously identified RsIA_CtaG/Cox11 and showed that infiltration of the recombinant protein into rice leaves caused disease-like symptoms. In the present study, we further characterized the functionality of RsIA_CtaG/Cox11. RsIA_CtaG/Cox11 is an alternative transcript of cytochrome c oxidase copper chaperone Cox11 that starts from the second AUG codon, but contains a functional secretion signal peptide. RNA interference with RsIA_CtaG/Cox11 reduced the pathogenicity of AG-1 IA towards rice and Nicotiana benthamiana without affecting its fitness or mycelial morphology. Transient expression of the RsIA_CtaG/Cox11-GFP "],"journal":["Molecular plant pathology"],"pubmed_title":["Mitochondrial-targeting effector RsIA_CtaG/Cox11 in Rhizoctonia solani AG-1 IA has two functions: plant immunity suppression and cell death induction mediated by a rice cytochrome c oxidase subunit."],"pmcid":["PMC10799210"],"funding_grant_id":["21H02197","2021-YF05-02326-SN","2019YFN0010","2021-GH02-00085-HZ","2020-YFH0161","18H02206","31400130","2014CB160304"],"pubmed_authors":["Yamamoto N","Yi X","Zhang D","Lin R","Okada K","Noutoshi Y","Zheng T","Liu Y","Zheng H","Lin H","Xiang X","Zheng A","Wang Z"],"additional_accession":[]},"is_claimable":false,"name":"Mitochondrial-targeting effector RsIA_CtaG/Cox11 in Rhizoctonia solani AG-1 IA has two functions: plant immunity suppression and cell death induction mediated by a rice cytochrome c oxidase subunit.","description":"Rhizoctonia solani AG-1 IA causes a necrotrophic rice disease and is a serious threat to rice production. To date, only a few effectors have been characterized in AG-1 IA. We previously identified RsIA_CtaG/Cox11 and showed that infiltration of the recombinant protein into rice leaves caused disease-like symptoms. In the present study, we further characterized the functionality of RsIA_CtaG/Cox11. RsIA_CtaG/Cox11 is an alternative transcript of cytochrome c oxidase copper chaperone Cox11 that starts from the second AUG codon, but contains a functional secretion signal peptide. RNA interference with RsIA_CtaG/Cox11 reduced the pathogenicity of AG-1 IA towards rice and Nicotiana benthamiana without affecting its fitness or mycelial morphology. Transient expression of the RsIA_CtaG/Cox11-GFP ","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Jan","modification":"2025-05-18T11:10:55.674Z","creation":"2024-10-17T21:57:38.12Z"},"accession":"S-EPMC10799210","cross_references":{"pubmed":["37902589"],"doi":["10.1111/mpp.13397"]}}