{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["57(2)"],"submitter":["Engel S"],"pubmed_abstract":["Soft polymer nanocapsules and microgels, which can adapt their shape and, at the same time, sequester and release molecular payloads in response to an external trigger, are a challenging complement to vesicular structures like polymersomes. In this work, we report the synthesis of such capsules by photo-cross-linking of coumarin-substituted polyglycidyl ethers, which we prepared by Williamson etherification of epichlorohydrin (ECH) repeating units with 7-hydroxycoumarin in copolymers with <i>tert</i>-butyl glycidyl ether (<i>t</i>BGE). To control capsule size, we employed the prepolymers in an o/w miniemulsion, where they formed a gel layer at the interface upon irradiation at 365 nm by [2π + 2π] photodimerization of the coumarin groups. Upon irradiation at 254 nm, the reaction could be re"],"journal":["Macromolecules"],"pagination":["707-718"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10810002"],"repository":["biostudies-literature"],"pubmed_title":["Photo-cross-linked and pH-Switchable Soft Polymer Nanocapsules from Polyglycidyl Ethers."],"pmcid":["PMC10810002"],"pubmed_authors":["Rose JC","Schafer D","Engel S","Jeschenko PM","Moller M","Keul H","Herres-Pawlis S","van Dongen M","Bruns M"],"additional_accession":[]},"is_claimable":false,"name":"Photo-cross-linked and pH-Switchable Soft Polymer Nanocapsules from Polyglycidyl Ethers.","description":"Soft polymer nanocapsules and microgels, which can adapt their shape and, at the same time, sequester and release molecular payloads in response to an external trigger, are a challenging complement to vesicular structures like polymersomes. In this work, we report the synthesis of such capsules by photo-cross-linking of coumarin-substituted polyglycidyl ethers, which we prepared by Williamson etherification of epichlorohydrin (ECH) repeating units with 7-hydroxycoumarin in copolymers with <i>tert</i>-butyl glycidyl ether (<i>t</i>BGE). To control capsule size, we employed the prepolymers in an o/w miniemulsion, where they formed a gel layer at the interface upon irradiation at 365 nm by [2π + 2π] photodimerization of the coumarin groups. Upon irradiation at 254 nm, the reaction could be re","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Jan","modification":"2025-04-25T23:33:20.925Z","creation":"2025-04-06T09:23:06.876Z"},"accession":"S-EPMC10810002","cross_references":{"pubmed":["38283123"],"doi":["10.1021/acs.macromol.3c01698"]}}