{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12(1)"],"submitter":["Sim TM"],"pubmed_abstract":["We recently reported that messenger ribonucleic acid (mRNA) coronavirus disease 2019 (COVID-19) vaccination was associated with flares in 9% of patients with systemic lupus erythematosus (SLE). Herein, we focused our analysis on patients from a multi-ethnic Southeast Asian lupus cohort with the intention of identifying distinct phenotypes associated with increased flares after mRNA COVID-19 vaccination.<h4>Methods</h4>Six hundred and thirty-three SLE patients from eight public healthcare institutions were divided into test and validation cohorts based on healthcare clusters. Latent class analysis was performed based on age, ethnicity, gender, vaccine type, past COVID-19 infection, interruption of immunomodulatory/immunosuppressive treatment for vaccination, disease activity and background "],"journal":["Vaccines"],"pagination":["29"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10819486"],"repository":["biostudies-literature"],"pubmed_title":["Latent Class Analysis Identifies Distinct Phenotypes of Systemic Lupus Erythematosus Predictive of Flares after mRNA COVID-19 Vaccination: Results from the Coronavirus National Vaccine Registry for ImmuNe Diseases SINGapore (CONVIN-SING)."],"pmcid":["PMC10819486"],"pubmed_authors":["Ma M","Arkachaisri T","Sriranganathan M","Poh YJ","Xu C","Chuah TY","Angkodjojo S","Tay SH","Tan TC","Cheung PP","Lahiri M","Phang KF","Mak A","Yap QV","Sim TM","Santosa A","Fong W","Roslan NE","Kong KO","Chan YH","Law A"],"additional_accession":[]},"is_claimable":false,"name":"Latent Class Analysis Identifies Distinct Phenotypes of Systemic Lupus Erythematosus Predictive of Flares after mRNA COVID-19 Vaccination: Results from the Coronavirus National Vaccine Registry for ImmuNe Diseases SINGapore (CONVIN-SING).","description":"We recently reported that messenger ribonucleic acid (mRNA) coronavirus disease 2019 (COVID-19) vaccination was associated with flares in 9% of patients with systemic lupus erythematosus (SLE). Herein, we focused our analysis on patients from a multi-ethnic Southeast Asian lupus cohort with the intention of identifying distinct phenotypes associated with increased flares after mRNA COVID-19 vaccination.<h4>Methods</h4>Six hundred and thirty-three SLE patients from eight public healthcare institutions were divided into test and validation cohorts based on healthcare clusters. Latent class analysis was performed based on age, ethnicity, gender, vaccine type, past COVID-19 infection, interruption of immunomodulatory/immunosuppressive treatment for vaccination, disease activity and background ","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Dec","modification":"2026-06-27T03:16:07.491Z","creation":"2024-11-08T15:58:21.327Z"},"accession":"S-EPMC10819486","cross_references":{"pubmed":["38250842"],"doi":["10.3390/vaccines12010029"]}}