{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Mauri G"],"funding":["Fondazione Oncologia Niguarda Onlus","Fondazione Regionale Ricerca Biomedica Regione Lombardia"],"pagination":["e885-e889"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10850832"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["13(e3)"],"pubmed_abstract":["<h4>Objectives</h4>Early-onset colorectal cancer (EO-CRC) incidence is increasing, raising a clinical challenge. Clinicians tend to treat EO-CRC patients with more intensive regimens despite the lack of survival benefits, based on an age-related bias. Limited evidence is available regarding treatment-related toxicities in this peculiar subset of patients.<h4>Methods</h4>We performed a literature search in MEDLINE/PubMed, EMBASE and Scopus, looking for reporting of nausea, vomiting and diarrhoea occurring in patients with EO-CRC, defined by age lower than 50 years old at initial diagnosis, while receiving anticancer treatment.<h4>Results</h4>2318 records were screened and 9 full-text articles were considered eligible for inclusion for a total of 59 783 patients (of whom 8681 EO-CRC patients"],"journal":["BMJ supportive & palliative care"],"pubmed_title":["Young-onset colorectal cancer: treatment-related nausea, vomiting and diarrhoea."],"pmcid":["PMC10850832"],"funding_grant_id":["CP 12/2018"],"pubmed_authors":["Siena S","Artale S","Sartore-Bianchi A","Bonazzina E","Pedrazzoli P","Mariano S","Serra F","Mauri G","Cavestro GM","Pedrani M","Ghezzi S","Bencardino K","Caccialanza R"],"additional_accession":[]},"is_claimable":false,"name":"Young-onset colorectal cancer: treatment-related nausea, vomiting and diarrhoea.","description":"<h4>Objectives</h4>Early-onset colorectal cancer (EO-CRC) incidence is increasing, raising a clinical challenge. Clinicians tend to treat EO-CRC patients with more intensive regimens despite the lack of survival benefits, based on an age-related bias. Limited evidence is available regarding treatment-related toxicities in this peculiar subset of patients.<h4>Methods</h4>We performed a literature search in MEDLINE/PubMed, EMBASE and Scopus, looking for reporting of nausea, vomiting and diarrhoea occurring in patients with EO-CRC, defined by age lower than 50 years old at initial diagnosis, while receiving anticancer treatment.<h4>Results</h4>2318 records were screened and 9 full-text articles were considered eligible for inclusion for a total of 59 783 patients (of whom 8681 EO-CRC patients","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Jan","modification":"2026-06-12T05:52:52.261Z","creation":"2026-06-12T03:08:26.868Z"},"accession":"S-EPMC10850832","cross_references":{"pubmed":["37344158"],"doi":["10.1136/spcare-2023-004203"]}}