{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Bushnell J"],"funding":["NIA NIH HHS","NIDCD NIH HHS","Alzheimer&apos;s Association","Alzheimer's Association","National Institute on Aging"],"pagination":["S29-S41"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10855009"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["19 Suppl 9"],"pubmed_abstract":["<h4>Introduction</h4>The Rey Auditory Verbal Learning Test (RAVLT) is a useful neuropsychological test for describing episodic memory impairment in dementia. However, there is limited research on its utility in early-onset Alzheimer's disease (EOAD). We assess the influence of amyloid and diagnostic syndrome on several memory scores in EOAD.<h4>Methods</h4>We transcribed RAVLT recordings from 303 subjects in the Longitudinal Early-Onset Alzheimer's Disease Study. Subjects were grouped by amyloid status and syndrome. Primacy, recency, J-curve, duration, stopping time, and speed score were calculated and entered into linear mixed effects models as dependent variables.<h4>Results</h4>Compared with amyloid negative subjects, positive subjects exhibited effects on raw score, primacy, recency, a"],"journal":["Alzheimer's & dementia : the journal of the Alzheimer's Association"],"pubmed_title":["Influence of amyloid and diagnostic syndrome on non-traditional memory scores in early-onset Alzheimer's disease."],"pmcid":["PMC10855009"],"funding_grant_id":["P30 AG010133","P30 AG062677","U01 AG057195","P30 AG066515","P30 AG072980","U24 AG021886","P30 AG066462","R56 AG057195","P30 AG072976","LDRFP‐21‐818464","P30 AG072977","K23 DC016912","P30 AG066444","LDRFP-21-818464","P30 AG072979","LDRFP‐21‐828356","U01 AG016976","P30 AG062421","P30 AG062422","LDRFP-21-828356","LDRFP-21-824473","P30 AG066506","P30 AG066507","LDRFP‐21‐824473","P30 AG066530","P30 AG066511","U24 AG072122"],"pubmed_authors":["Dage JL","Apostolova LG","Musiek E","Salloway S","Jack CR","Mundada NS","Touroutoglou A","Day GS","Turner RS","Rumbaugh M","Kukull WA","Graff-Radford NR","Wolk DA","Koeppe R","Honig LS","Jones DT","Riddle M","Rogalski E","Carrillo MC","Clark DG","Hammers DB","La Joie R","Rabinovici GD","Aisen P","Kirby K","Soleimani-Meigooni DN","Murray ME","Mendez M","Grinberg LT","Foroud T","Atri A","Nudelman K","Duara R","Eloyan A","Dickerson BC","Wingo TS","Bushnell J","Toga A","Onyike CU","Masdeu J","Iaccarino L","Sha S","LEADS Consortium","Kramer J","Vemuri P"],"additional_accession":[]},"is_claimable":false,"name":"Influence of amyloid and diagnostic syndrome on non-traditional memory scores in early-onset Alzheimer's disease.","description":"<h4>Introduction</h4>The Rey Auditory Verbal Learning Test (RAVLT) is a useful neuropsychological test for describing episodic memory impairment in dementia. However, there is limited research on its utility in early-onset Alzheimer's disease (EOAD). We assess the influence of amyloid and diagnostic syndrome on several memory scores in EOAD.<h4>Methods</h4>We transcribed RAVLT recordings from 303 subjects in the Longitudinal Early-Onset Alzheimer's Disease Study. Subjects were grouped by amyloid status and syndrome. Primacy, recency, J-curve, duration, stopping time, and speed score were calculated and entered into linear mixed effects models as dependent variables.<h4>Results</h4>Compared with amyloid negative subjects, positive subjects exhibited effects on raw score, primacy, recency, a","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Nov","modification":"2025-04-18T13:00:22.212Z","creation":"2025-04-06T22:28:03.426Z"},"accession":"S-EPMC10855009","cross_references":{"pubmed":["37653686"],"doi":["10.1002/alz.13434"]}}