biostudies-literatureUnknown26(2)Boos CJThe ambulatory arterial stiffness index (AASI) is a novel measure of both blood pressure (BP) variability and arterial stiffness. This systematic review and meta-analysis was designed to evaluate the strength of the association between AASI and mortality and major adverse cardiovascular events (MACE). PubMed, Scopus, CINAHL, Google Scholar. and the Cochrane library were searched for relevant studies to July 31, 2023. Two investigators independently extracted data. The Newcastle-Ottawa Scale (NOS) was used to assess the quality of all included articles. The relationship between baseline AASI and outcomes were examined using relative risk (RR) ratios with 95% confidence intervals (CI) with RevMan web. Thirteen studies were included and representing 28 855 adult patients who were followed up Journal of clinical hypertension (Greenwich, Conn.)89-101https://www.ebi.ac.uk/biostudies/studies/S-EPMC10857461biostudies-literatureAmbulatory arterial stiffness index, mortality, and adverse cardiovascular outcomes; Systematic review and meta-analysis.PMC10857461Boos CJKhattab AHein AfalseAmbulatory arterial stiffness index, mortality, and adverse cardiovascular outcomes; Systematic review and meta-analysis.The ambulatory arterial stiffness index (AASI) is a novel measure of both blood pressure (BP) variability and arterial stiffness. This systematic review and meta-analysis was designed to evaluate the strength of the association between AASI and mortality and major adverse cardiovascular events (MACE). PubMed, Scopus, CINAHL, Google Scholar. and the Cochrane library were searched for relevant studies to July 31, 2023. Two investigators independently extracted data. The Newcastle-Ottawa Scale (NOS) was used to assess the quality of all included articles. The relationship between baseline AASI and outcomes were examined using relative risk (RR) ratios with 95% confidence intervals (CI) with RevMan web. Thirteen studies were included and representing 28 855 adult patients who were followed up 2024-01-01T00:00:00Z2024 Feb2025-04-05T00:02:11.355Z2025-04-05T00:02:11.355ZS-EPMC108574613823420610.1111/jch.14755