biostudies-literatureTsurkalenko OFonds National de la Recherche LuxembourgHorizon 2020André Losch Fondation179https://www.ebi.ac.uk/biostudies/studies/S-EPMC10858600biostudies-literatureUnknown24(1)<h4>Background</h4>During the COVID-19 pandemic swift implementation of research cohorts was key. While many studies focused exclusively on infected individuals, population based cohorts are essential for the follow-up of SARS-CoV-2 impact on public health. Here we present the CON-VINCE cohort, estimate the point and period prevalence of the SARS-CoV-2 infection, reflect on the spread within the Luxembourgish population, examine immune responses to SARS-CoV-2 infection and vaccination, and ascertain the impact of the pandemic on population psychological wellbeing at a nationwide level.<h4>Methods</h4>A representative sample of the adult Luxembourgish population was enrolled. The cohort was followed-up for twelve months. SARS-CoV-2 RT-qPCR and serology were conducted at each sampling visit.BMC infectious diseasesCreation of a pandemic memory by tracing COVID-19 infections and immunity in Luxembourg (CON-VINCE).PMC1085860010101616714716281/ CONVINCE/ KrugerAmmerlaan WPirard MFMeyrath MHilger CTrung NBellora CLutz ANeumann MLehmann SLemaire Mdi Pinto PWeibel EGroues VKhurmin PGorgogietas VHerkenne ESandt EGawron PMinelli MAssele-Kama AWauters FAbdelrahman THanff AMMassart FCauchie HMDi Pasquale APenny CLeick MMarchese MDourson JLSantos BBrenner DHuiart LBeckers LCounson MHemedan ABeaupain NHamot GBiver LHenry ELopes AFPerquin MSchroder VEKlucken JFournier GNicolai BHeirendt LMuhlschlegel FServais JYRemark LSeal SStute LHubschen JMousel ATurner JPexaras ACharalambous ECharpentier ESchweicher AMay PBeaumont KRump KCoito SKlein TFautsch TSchneider RKolodkin AToll SRamos BGTrouet JKlein FZamboni TGhosh SToukourou NMunsch MGraas JKruger RHenry MSimon FDording CLeist AAncien FOlesky CBoly SFerrandon TLambert PMoreno CVAguayo GASkrozic AO'Sullivan MPGeorges LSnoeck CSokolowska KOllert MSchmitt MEsteves DVSchumacher SWalczak CGidenne SCoibion EPlesseria JMWang XSausy AThien HSatagopam VCON-VINCE consortium and the ORCHESTRA working groupIserentant GJagi PBulaev DMarques TLoureiro JMGlaab EKaysen AFritz JVRommes BHerzinger SVogele COgorzaly LDomingues OHundt ATrefois CDragomir BAlper POhnmacht JTsurkalenko OKler SRauschenberger APavelka LCollart DGantenbein MMeriaux SAcharya GGomes CPCDe Witt BRodriguez ALebioda JJVyas MPauly LGu WNguyen TPauly CLumley ABahlawane CWeber BVerschueren CBetsou FMeyers GRFerrand JYHansen LVaillant MHefele LSchmitt CHansen MfalseCreation of a pandemic memory by tracing COVID-19 infections and immunity in Luxembourg (CON-VINCE).<h4>Background</h4>During the COVID-19 pandemic swift implementation of research cohorts was key. While many studies focused exclusively on infected individuals, population based cohorts are essential for the follow-up of SARS-CoV-2 impact on public health. Here we present the CON-VINCE cohort, estimate the point and period prevalence of the SARS-CoV-2 infection, reflect on the spread within the Luxembourgish population, examine immune responses to SARS-CoV-2 infection and vaccination, and ascertain the impact of the pandemic on population psychological wellbeing at a nationwide level.<h4>Methods</h4>A representative sample of the adult Luxembourgish population was enrolled. The cohort was followed-up for twelve months. SARS-CoV-2 RT-qPCR and serology were conducted at each sampling visit.2024-01-01T00:00:00Z2024 Feb2026-06-01T11:19:28.789Z2026-04-08T11:44:00.946ZS-EPMC108586003833664910.1186/s12879-024-09055-z