{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Saleh MG"],"funding":["NICHD NIH HHS","NIBIB NIH HHS","NCCIH NIH HHS","NIDA NIH HHS","NIH","NIH HHS"],"pagination":["1314-1322"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10865745"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["91(4)"],"pubmed_abstract":["<h4>Purpose</h4>To demonstrate J-difference coediting of glutamate using Hadamard encoding and reconstruction of Mescher-Garwood-edited spectroscopy (HERMES).<h4>Methods</h4>Density-matrix simulations of HERMES (TE 80 ms) and 1D J-resolved (TE 31-229 ms) of glutamate (Glu), glutamine (Gln), γ-aminobutyric acid (GABA), and glutathione (GSH) were performed. HERMES comprised four sub-experiments with editing pulses applied as follows: (A) 1.9/4.56 ppm simultaneously (ON<sub>GABA</sub> /ON<sub>GSH</sub> ); (B) 1.9 ppm only (ON<sub>GABA</sub> /OFF<sub>GSH</sub> ); (C) 4.56 ppm only (OFF<sub>GABA</sub> /ON<sub>GSH</sub> ); and (D) 7.5 ppm (OFF<sub>GABA</sub> /OFF<sub>GSH</sub> ). Phantom HERMES and 1D J-resolved experiments of Glu were performed. Finally, in vivo HERMES (20-ms editing pulses) an"],"journal":["Magnetic resonance in medicine"],"pubmed_title":["Glutamate measurements using edited MRS."],"pmcid":["PMC10865745"],"funding_grant_id":["R01 EB016089","U01 DA041117","P50 HD105354","R01EB016089","R00DA051315","P50 HD103538","U01DA041117","K99 DA051315","R21 AT010736","U01DA041134","U01 DA041134","R01EB023963","R21 DA047673","R21DA047673","P41EB031771","P41 EB031771","R01 EB023963","R00 DA051315"],"pubmed_authors":["Saleh MG","Chang L","Cunningham E","Cloak C","Renshaw PF","Edden RAE","Zollner HJ","Prescot A","Subramaniam P","Yurgelun-Todd D","Ernst T","Roberts TPL"],"additional_accession":[]},"is_claimable":false,"name":"Glutamate measurements using edited MRS.","description":"<h4>Purpose</h4>To demonstrate J-difference coediting of glutamate using Hadamard encoding and reconstruction of Mescher-Garwood-edited spectroscopy (HERMES).<h4>Methods</h4>Density-matrix simulations of HERMES (TE 80 ms) and 1D J-resolved (TE 31-229 ms) of glutamate (Glu), glutamine (Gln), γ-aminobutyric acid (GABA), and glutathione (GSH) were performed. HERMES comprised four sub-experiments with editing pulses applied as follows: (A) 1.9/4.56 ppm simultaneously (ON<sub>GABA</sub> /ON<sub>GSH</sub> ); (B) 1.9 ppm only (ON<sub>GABA</sub> /OFF<sub>GSH</sub> ); (C) 4.56 ppm only (OFF<sub>GABA</sub> /ON<sub>GSH</sub> ); and (D) 7.5 ppm (OFF<sub>GABA</sub> /OFF<sub>GSH</sub> ). Phantom HERMES and 1D J-resolved experiments of Glu were performed. Finally, in vivo HERMES (20-ms editing pulses) an","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Apr","modification":"2025-06-25T03:04:27.44Z","creation":"2025-06-25T03:04:27.44Z"},"accession":"S-EPMC10865745","cross_references":{"pubmed":["38044723"],"doi":["10.1002/mrm.29929"]}}