biostudies-literatureUnknown15Lee TH<h4>Background</h4>Stroke burden is largely due to long-term impairments requiring prolonged care with loss of productivity. We aimed to identify and assess studies of different registered pharmacological therapies as treatments to improve post-stroke impairments and/or disabilities.<h4>Methods</h4>We performed a systematic-search-and-review of treatments that have been investigated as recovery-enhancing or recovery-promoting therapies in adult patients with stroke. The treatment must have received registration or market authorization in any country regardless of primary indication. Outcomes included in the review were neurological impairments and functional/disability assessments. "The best available studies" based on study design, study size, and/or date of publication were selected and Frontiers in neurology1346177https://www.ebi.ac.uk/biostudies/studies/S-EPMC10866005biostudies-literatureA systematic-search-and-review of registered pharmacological therapies investigated to improve neuro-recovery after a stroke.PMC10866005Guo LAsian Stroke Advisory PanelPandian JLee THTan KSUchiyama SVenketasubramanian NKusuma YChiu HCNavarro JCWong YfalseA systematic-search-and-review of registered pharmacological therapies investigated to improve neuro-recovery after a stroke.<h4>Background</h4>Stroke burden is largely due to long-term impairments requiring prolonged care with loss of productivity. We aimed to identify and assess studies of different registered pharmacological therapies as treatments to improve post-stroke impairments and/or disabilities.<h4>Methods</h4>We performed a systematic-search-and-review of treatments that have been investigated as recovery-enhancing or recovery-promoting therapies in adult patients with stroke. The treatment must have received registration or market authorization in any country regardless of primary indication. Outcomes included in the review were neurological impairments and functional/disability assessments. "The best available studies" based on study design, study size, and/or date of publication were selected and 2024-01-01T00:00:00Z20242025-04-21T15:16:01.07Z2024-11-14T13:29:23.489ZS-EPMC108660053835689010.3389/fneur.2024.1346177