biostudies-literatureUnknown14Kao TW<h4>Background</h4>Primary aldosteronism (PA) has been associated with atherosclerosis beyond the extent of essential hypertension, but the impact of albuminuria remains unknown.<h4>Objective</h4>To investigate the effect of concomitant albuminuria on arterial stiffness in PA.<h4>Design</h4>Prospective cohort study.<h4>Methods</h4>A prospective cohort study was conducted to evaluate the association of albuminuria (>30 mg/g in morning spot urine) with arterial stiffness, as measured non-invasively by pulse wave velocity (PWV) in patients with PA. Propensity score matching (PSM) with age, sex, diabetes, systolic and diastolic blood pressure, creatinine, potassium, number of antihypertensive medications, and hypertension history was used to balance baseline characteristics. The effects of albTherapeutic advances in chronic disease20406223231210114https://www.ebi.ac.uk/biostudies/studies/S-EPMC10867404biostudies-literatureSynergistic effect of albuminuria on atherosclerosis in patients with primary aldosteronism.PMC10867404Huang KHChueh JSHuang WCKao TWHung CSWu VCTsai CHChang YYChang CCLu CCChan CKChen ZWLin YHLee BCLiao CWPan CTLai TSfalseSynergistic effect of albuminuria on atherosclerosis in patients with primary aldosteronism.<h4>Background</h4>Primary aldosteronism (PA) has been associated with atherosclerosis beyond the extent of essential hypertension, but the impact of albuminuria remains unknown.<h4>Objective</h4>To investigate the effect of concomitant albuminuria on arterial stiffness in PA.<h4>Design</h4>Prospective cohort study.<h4>Methods</h4>A prospective cohort study was conducted to evaluate the association of albuminuria (>30 mg/g in morning spot urine) with arterial stiffness, as measured non-invasively by pulse wave velocity (PWV) in patients with PA. Propensity score matching (PSM) with age, sex, diabetes, systolic and diastolic blood pressure, creatinine, potassium, number of antihypertensive medications, and hypertension history was used to balance baseline characteristics. The effects of alb2023-01-01T00:00:00Z20232025-04-05T09:05:41.758Z2024-11-14T18:14:05.793ZS-EPMC108674043836200710.1177/20406223231210114