biostudies-literatureJokanovic NAustralian Government Medical Research Future Funddlae016https://www.ebi.ac.uk/biostudies/studies/S-EPMC10873136biostudies-literatureUnknown6(1)<h4>Objectives</h4>To evaluate the need and feasibility of a nurse-led antimicrobial stewardship (AMS) programme in two Australian residential aged care homes (RACHs) to inform a stepped-wedged, cluster randomized controlled trial (SW-cRCT).<h4>Methods</h4>A mixed-methods pilot study of a nurse-led AMS programme was performed in two RACHs in Victoria, Australia (July-December 2019). The AMS programme comprised education, infection assessment and management guidelines, and documentation to support appropriate antimicrobial use in urinary, lower respiratory and skin/soft tissue infections. The programme was implemented over three phases: (i) pre-implementation education and integration (1 month); (ii) implementation of the intervention (3 months); and (iii) post-intervention evaluation (1 moJAC-antimicrobial resistancePilot study to evaluate the need and implementation of a multifaceted nurse-led antimicrobial stewardship intervention in residential aged care.PMC10873136GNT1152342Jeon YHStuart RSTART Trial GroupTsindos TWatson EPeel TNPeleg AWisniewski JStuart RLAyton DHaines TDe Maio NPeleg AYCheng ACCruickshank MJokanovic NLee SJCheng ATrauer JRoney JStewardson AJHolt KPeel THilmer SNWilson DTravis LStewardson AHilmer SfalsePilot study to evaluate the need and implementation of a multifaceted nurse-led antimicrobial stewardship intervention in residential aged care.<h4>Objectives</h4>To evaluate the need and feasibility of a nurse-led antimicrobial stewardship (AMS) programme in two Australian residential aged care homes (RACHs) to inform a stepped-wedged, cluster randomized controlled trial (SW-cRCT).<h4>Methods</h4>A mixed-methods pilot study of a nurse-led AMS programme was performed in two RACHs in Victoria, Australia (July-December 2019). The AMS programme comprised education, infection assessment and management guidelines, and documentation to support appropriate antimicrobial use in urinary, lower respiratory and skin/soft tissue infections. The programme was implemented over three phases: (i) pre-implementation education and integration (1 month); (ii) implementation of the intervention (3 months); and (iii) post-intervention evaluation (1 mo2024-01-01T00:00:00Z2024 Feb2026-07-15T02:16:44.938Z2025-02-19T01:42:07.437ZS-EPMC108731363837199910.1093/jacamr/dlae016