biostudies-literatureUnknown26Bargeri S<h4>Background</h4>Several systematic reviews (SRs) assessing the use of telemedicine for musculoskeletal conditions have been published in recent years. However, the landscape of evidence on multiple clinical outcomes remains unclear.<h4>Objective</h4>We aimed to summarize the available evidence from SRs on telemedicine for musculoskeletal disorders.<h4>Methods</h4>We conducted an umbrella review of SRs with and without meta-analysis by searching PubMed and EMBASE up to July 25, 2022, for SRs of randomized controlled trials assessing telemedicine. We collected any kind of patient-reported outcome measures (PROMs), patient-reported experience measures (PREMs), and objective measures, including direct and indirect costs. We assessed the methodological quality with the AMSTAR 2 tool (A MeasuJournal of medical Internet researche50090https://www.ebi.ac.uk/biostudies/studies/S-EPMC10873802biostudies-literatureEffectiveness of Telemedicine for Musculoskeletal Disorders: Umbrella Review.PMC10873802Castellini GBanfi GPennestri FGuida SGianola SBargeri SVitale JAfalseEffectiveness of Telemedicine for Musculoskeletal Disorders: Umbrella Review.<h4>Background</h4>Several systematic reviews (SRs) assessing the use of telemedicine for musculoskeletal conditions have been published in recent years. However, the landscape of evidence on multiple clinical outcomes remains unclear.<h4>Objective</h4>We aimed to summarize the available evidence from SRs on telemedicine for musculoskeletal disorders.<h4>Methods</h4>We conducted an umbrella review of SRs with and without meta-analysis by searching PubMed and EMBASE up to July 25, 2022, for SRs of randomized controlled trials assessing telemedicine. We collected any kind of patient-reported outcome measures (PROMs), patient-reported experience measures (PREMs), and objective measures, including direct and indirect costs. We assessed the methodological quality with the AMSTAR 2 tool (A Measu2024-01-01T00:00:00Z2024 Feb2026-06-09T07:13:21.467Z2025-04-20T04:02:50.732ZS-EPMC108738023830615610.2196/50090