biostudies-literatureSang WTalents Training Program of Shanghai Pudong HospitalMultidisciplinary Team for Urinary Incontinence and Pelvic Floor DiseasesMajor Weak Discipline Construction Project of Pudong Health and Family Planning Commission of Shanghai43https://www.ebi.ac.uk/biostudies/studies/S-EPMC10874573biostudies-literatureUnknown24(1)Peritoneal loose body (PLB) is a kind of lesions located in the abdominal cavity or pelvic cavity, which is rare and difficult to diagnose. The diameter of PLB is mostly 0.5-2.5 cm. Most PLBS are asymptomatic. Here we reported a case of giant PLB in the pelvis and analyzed its structure and protein composition. Surgical exploration revealed a white oval mass (4.5*4*3 cm) in the pelvic cavity. After the mass was removed, the symptoms of hematuria disappeared and the patient was discharged on the second postoperative day. Histochemical staining showed that PLB was mainly composed of collagen and scattered calcification. The protein components of PLB were detected by proteome analysis, and a variety of proteins related to collagen deposition and calcification were identified in PLB.BMC urologyGiant peritoneal loose body and its protein composition: a case report.PMC10874573No. PWZbr2022-20MDT2021-06No. LJ202203Sang WLi YHong XQu HYi QZhu RfalseGiant peritoneal loose body and its protein composition: a case report.Peritoneal loose body (PLB) is a kind of lesions located in the abdominal cavity or pelvic cavity, which is rare and difficult to diagnose. The diameter of PLB is mostly 0.5-2.5 cm. Most PLBS are asymptomatic. Here we reported a case of giant PLB in the pelvis and analyzed its structure and protein composition. Surgical exploration revealed a white oval mass (4.5*4*3 cm) in the pelvic cavity. After the mass was removed, the symptoms of hematuria disappeared and the patient was discharged on the second postoperative day. Histochemical staining showed that PLB was mainly composed of collagen and scattered calcification. The protein components of PLB were detected by proteome analysis, and a variety of proteins related to collagen deposition and calcification were identified in PLB.2024-01-01T00:00:00Z2024 Feb2025-05-31T23:28:16.602Z2025-05-31T23:28:16.602ZS-EPMC108745733836833010.1186/s12894-024-01425-8