{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["69"],"submitter":["Guo J"],"funding":["The University of Hong Kong","Shenzhen Science and Technology Innovation Commission","China Academy of Chinese Medical Sciences","University Grants Committee Research Grants Council"],"pubmed_abstract":["Background
Diabetic kidney disease (DKD) is a leading cause of end-stage kidney disease and is associated with high mortality rates. The influence of routine clinical parameters on DKD onset in patients with type 2 diabetes mellitus (T2DM) remains uncertain.Methods
In this systematic review and meta-analysis, we searched multiple databases, including PubMed, Embase, Scopus, Web of Science, and Cochrane Library, for studies published from each database inception until January 11, 2024. We included cohort studies examining the association between DKD onset and various clinical parameters, including body mass index (BMI), hemoglobin A1c (HbA1c), systolic blood pressure (SBP), diastolic blood pressure (DBP), total cholesterol (TC), triglycerides (TG), low-density lipoprotein (L"],"journal":["EClinicalMedicine"],"pagination":["102482"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10875261"],"repository":["biostudies-literature"],"pubmed_title":["Dose-response association of diabetic kidney disease with routine clinical parameters in patients with type 2 diabetes mellitus: a systematic review and meta-analysis."],"pmcid":["PMC10875261"],"pubmed_authors":["Li H","Wang A","Lu X","Zhang H","Leung CL","Li F","Lau NC","Chen H","Shao B","He Q","Fong TL","Wang J","Meng X","Chia XW","Guo J","Liu C","Wang Y"],"additional_accession":[]},"is_claimable":false,"name":"Dose-response association of diabetic kidney disease with routine clinical parameters in patients with type 2 diabetes mellitus: a systematic review and meta-analysis.","description":"Background
Diabetic kidney disease (DKD) is a leading cause of end-stage kidney disease and is associated with high mortality rates. The influence of routine clinical parameters on DKD onset in patients with type 2 diabetes mellitus (T2DM) remains uncertain.Methods
In this systematic review and meta-analysis, we searched multiple databases, including PubMed, Embase, Scopus, Web of Science, and Cochrane Library, for studies published from each database inception until January 11, 2024. We included cohort studies examining the association between DKD onset and various clinical parameters, including body mass index (BMI), hemoglobin A1c (HbA1c), systolic blood pressure (SBP), diastolic blood pressure (DBP), total cholesterol (TC), triglycerides (TG), low-density lipoprotein (L","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Mar","modification":"2026-06-09T07:04:46.669Z","creation":"2025-04-04T14:00:49.418Z"},"accession":"S-EPMC10875261","cross_references":{"pubmed":["38374967"],"doi":["10.1016/j.eclinm.2024.102482"]}}