biostudies-literatureUnknown21Jiang XThe primary objective of this research was to investigate the effects of fermented <i>Auricularia cornea</i> var. Li<i>.</i>/blueberry (FACB) on the gut microbiota of these super-large mouse models. The study, found that the groups who were given different amounts of FACB saw a significant reduction in their triglyceride and total cholesterol levels. There was a noteworthy increase in the ranks of high-density lipoprotein cholesterol (HDL-C) (P < 0.05). Furthermore, it was noted that FACB influenced the gut microbiota of the obese rats, improving in both the variety and quantity of short-chain fatty acids present in their intestines. This research provided the inaugural evidence of FACB's potential as an effective anti-obesity agent in a high-fat diet model, implying it could serve as a prFood chemistry: X101160https://www.ebi.ac.uk/biostudies/studies/S-EPMC10876580biostudies-literaturePotential mechanism of probiotic fermentation of <i>Auricularia cornea</i> var. Li./blueberry to reduce obesity induced by a high-fat diet.PMC10876580Wang MLi XHe SLiu JFan WLi SJiang XZhao YfalsePotential mechanism of probiotic fermentation of <i>Auricularia cornea</i> var. Li./blueberry to reduce obesity induced by a high-fat diet.The primary objective of this research was to investigate the effects of fermented <i>Auricularia cornea</i> var. Li<i>.</i>/blueberry (FACB) on the gut microbiota of these super-large mouse models. The study, found that the groups who were given different amounts of FACB saw a significant reduction in their triglyceride and total cholesterol levels. There was a noteworthy increase in the ranks of high-density lipoprotein cholesterol (HDL-C) (P < 0.05). Furthermore, it was noted that FACB influenced the gut microbiota of the obese rats, improving in both the variety and quantity of short-chain fatty acids present in their intestines. This research provided the inaugural evidence of FACB's potential as an effective anti-obesity agent in a high-fat diet model, implying it could serve as a pr2024-01-01T00:00:00Z2024 Mar2025-04-22T11:02:14.84Z2025-04-05T23:51:14.458ZS-EPMC108765803837980610.1016/j.fochx.2024.101160