{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Patterson T"],"funding":["British Heart Foundation","National Institute for Health and Care Research"],"pagination":["1329-1337"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10877072"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["402(10410)"],"pubmed_abstract":["<h4>Background</h4>The International Liaison Committee on Resuscitation has called for a randomised trial of delivery to a cardiac arrest centre. We aimed to assess whether expedited delivery to a cardiac arrest centre compared with current standard of care following resuscitated cardiac arrest reduces deaths.<h4>Methods</h4>ARREST is a prospective, parallel, multicentre, open-label, randomised superiority trial. Patients (aged ≥18 years) with return of spontaneous circulation following out-of-hospital cardiac arrest without ST elevation were randomly assigned (1:1) at the scene of their cardiac arrest by London Ambulance Service staff using a secure online randomisation system to expedited delivery to the cardiac catheter laboratory at one of seven cardiac arrest centres or standard of ca"],"journal":["Lancet (London, England)"],"pubmed_title":["Expedited transfer to a cardiac arrest centre for non-ST-elevation out-of-hospital cardiac arrest (ARREST): a UK prospective, multicentre, parallel, randomised clinical trial."],"pmcid":["PMC10877072"],"funding_grant_id":["CS/16/3/32615"],"pubmed_authors":["Pavlidis A","Stephens N","Clapp B","Roberts P","Lane G","Nolan JP","Wragg A","Nijjer S","Wilson K","Dodd M","Perkins A","Mellett-Smith A","Pendolino V","Evans R","Jain A","Redwood SR","Perera D","Hughes J","Rosser G","Connor M","Bogle R","Kwok M","MacCarthy P","McCrone P","Byrne J","Blows L","Spencer O","Chamberlain D","Sidney T","Prendergast B","Long A","Perkins GD","Robertson S","Ozkor M","Das R","Kurbaan A","Clayton T","Rakhit R","Jerome L","Whitbread M","Muir K","Shaw J","Ritches-Price J","Petzer E","Kearney J","Webb I","Firoozi S","Curzen N","Lampard A","Malik I","Bannister C","Mamas M","ARREST trial collaborators","Morris T","Marciniak M","De Belder M","Patterson T","Wood D","Bell R","Brown M","Knight M","Khan M","Palti G","Stables R","Adamson D","Dalby M","Papadopoulos D","Fothergill RT"],"additional_accession":[]},"is_claimable":false,"name":"Expedited transfer to a cardiac arrest centre for non-ST-elevation out-of-hospital cardiac arrest (ARREST): a UK prospective, multicentre, parallel, randomised clinical trial.","description":"<h4>Background</h4>The International Liaison Committee on Resuscitation has called for a randomised trial of delivery to a cardiac arrest centre. We aimed to assess whether expedited delivery to a cardiac arrest centre compared with current standard of care following resuscitated cardiac arrest reduces deaths.<h4>Methods</h4>ARREST is a prospective, parallel, multicentre, open-label, randomised superiority trial. Patients (aged ≥18 years) with return of spontaneous circulation following out-of-hospital cardiac arrest without ST elevation were randomly assigned (1:1) at the scene of their cardiac arrest by London Ambulance Service staff using a secure online randomisation system to expedited delivery to the cardiac catheter laboratory at one of seven cardiac arrest centres or standard of ca","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Oct","modification":"2025-04-22T11:11:45.124Z","creation":"2025-04-05T23:51:40.54Z"},"accession":"S-EPMC10877072","cross_references":{"pubmed":["37647928"],"doi":["10.1016/S0140-6736(23)01351-X"]}}