{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["31(1)"],"submitter":["Clark GR"],"pubmed_abstract":["<h4>Objective</h4>To compare interval cancer proportions (ICP) in the faecal immunochemical test (FIT)-based Scottish Bowel Screening Programme (SBoSP) with the former guaiac faecal occult blood test (gFOBT)-based SBoSP and investigate associations between interval cancer (IC) and faecal haemoglobin concentration (f-Hb) threshold, sex, age, deprivation, site, and stage.<h4>Methods</h4>The ICP data from first year of the FIT-based SBoSP and the penultimate year of the gFOBT-based SBoSP were compared in a prospective cohort design.<h4>Results</h4>With FIT, 801 colorectal cancers (CRCs) were screen detected (SDC), 802 were in non-participants, 548 were ICs, 39 were colonoscopy missed and 72 were diagnosed after incomplete screening; with gFOBT: 540, 904, 556, 45, and 13, respectively. FIT had"],"journal":["Journal of medical screening"],"pagination":["21-27"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10878005"],"repository":["biostudies-literature"],"pubmed_title":["Interval cancers in a national colorectal screening programme based on faecal immunochemical testing: Implications for faecal haemoglobin concentration threshold and sex inequality."],"pmcid":["PMC10878005"],"pubmed_authors":["Godfrey T","Fraser CG","Clark GR","Purdie C","Strachan J","Carey FA","Steele RJ"],"additional_accession":[]},"is_claimable":false,"name":"Interval cancers in a national colorectal screening programme based on faecal immunochemical testing: Implications for faecal haemoglobin concentration threshold and sex inequality.","description":"<h4>Objective</h4>To compare interval cancer proportions (ICP) in the faecal immunochemical test (FIT)-based Scottish Bowel Screening Programme (SBoSP) with the former guaiac faecal occult blood test (gFOBT)-based SBoSP and investigate associations between interval cancer (IC) and faecal haemoglobin concentration (f-Hb) threshold, sex, age, deprivation, site, and stage.<h4>Methods</h4>The ICP data from first year of the FIT-based SBoSP and the penultimate year of the gFOBT-based SBoSP were compared in a prospective cohort design.<h4>Results</h4>With FIT, 801 colorectal cancers (CRCs) were screen detected (SDC), 802 were in non-participants, 548 were ICs, 39 were colonoscopy missed and 72 were diagnosed after incomplete screening; with gFOBT: 540, 904, 556, 45, and 13, respectively. FIT had","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Mar","modification":"2026-06-18T04:45:55.924Z","creation":"2025-04-05T23:49:58.798Z"},"accession":"S-EPMC10878005","cross_references":{"pubmed":["37469171"],"doi":["10.1177/09691413231188252"]}}