biostudies-literatureKjær BHFonden for Almen PraksisCopenhagen UniversityBispebjerg HospitalLundbeck FoundationRegion HovedstadenGigtforeningenDanske Fysioterapeuter135https://www.ebi.ac.uk/biostudies/studies/S-EPMC10880378biostudies-literatureUnknown25(1)<h4>Background</h4>Rotator cuff (RC) tendinopathy is the most reported shoulder disorder in the general population with highest prevalence in overhead athletes and adult working-age population. A growing body of evidence support exercise therapy as an effective intervention, but to date there are no prospective randomized controlled trials addressing pain as an intervention variable.<h4>Methods</h4>A single-site, prospective, pragmatic, assessor-blinded randomized controlled superiority trial. Eighty-four patients aged 18-55 years with chronic (symptom duration over 3 months) RC tendinopathy are randomized 1:1 to receive shoulder exercise during which pain is either allowed or avoided. The intervention period lasts 26 weeks. During that period, participants in both groups are offered 8 indTrialsTo allow or avoid pain during shoulder rehabilitation exercises for patients with chronic rotator cuff tendinopathy-Study protocol for a randomized controlled trial (the PASE trial).PMC10880378no numberA3588R192-A6751Internal fundA6932Cools AMJohannsen FETrostrup JMagnusson PSKjær BHBieler TSiersma VfalseTo allow or avoid pain during shoulder rehabilitation exercises for patients with chronic rotator cuff tendinopathy-Study protocol for a randomized controlled trial (the PASE trial).<h4>Background</h4>Rotator cuff (RC) tendinopathy is the most reported shoulder disorder in the general population with highest prevalence in overhead athletes and adult working-age population. A growing body of evidence support exercise therapy as an effective intervention, but to date there are no prospective randomized controlled trials addressing pain as an intervention variable.<h4>Methods</h4>A single-site, prospective, pragmatic, assessor-blinded randomized controlled superiority trial. Eighty-four patients aged 18-55 years with chronic (symptom duration over 3 months) RC tendinopathy are randomized 1:1 to receive shoulder exercise during which pain is either allowed or avoided. The intervention period lasts 26 weeks. During that period, participants in both groups are offered 8 ind2024-01-01T00:00:00Z2024 Feb2026-07-15T03:00:08.064Z2025-04-04T07:49:04.96ZS-EPMC108803783838345910.1186/s13063-024-07973-6