{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Stanton AM"],"funding":["South African Department of Science and Innovation, South African Medical Research Council and South African Population Research Infrastructure Network","South African Research Chairs Initiative, the Victor Daitz Foundation and the Sub-Saharan African Network for TB/HIV Research Excellence (SANTHE), a DELTAS Africa Initiative","NIAID NIH HHS","NIMH, National Institutes of Health","Africa Health Research Institute","NIMH NIH HHS","NHLBI NIH HHS","NIAID, National Institutes of Health","Bill and Melinda Gates Foundation","Wellcome Trust","NHLBI, National Institutes of Health","New Partnership for Africa’s Development Planning and Coordinating Agency"],"pagination":["e0293963"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10880982"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["19(2)"],"pubmed_abstract":["Health-related quality of life (HRQoL) assesses the perceived impact of health status across life domains. Although research has explored the relationship between specific conditions, including HIV, and HRQoL in low-resource settings, less attention has been paid to the association between multimorbidity and HRQoL. In a secondary analysis of cross-sectional data from the Vukuzazi (\"Wake up and know ourselves\" in isiZulu) study, which identified the prevalence and overlap of non-communicable and infectious diseases in the uMkhanyakunde district of KwaZulu-Natal, we (1) evaluated the impact of multimorbidity on HRQoL; (2) determined the relative associations among infectious diseases, non-communicable diseases (NCDs), and HRQoL; and (3) examined the effects of controlled versus non-controlle"],"journal":["PloS one"],"pubmed_title":["HIV, multimorbidity, and health-related quality of life in rural KwaZulu-Natal, South Africa: A population-based study."],"pmcid":["PMC10880982"],"funding_grant_id":["K24 HL166024","K08AI118538","OPP1175182","201433/Z/16/Z","K23MH131438","DEL-15-006","K23 MH131438","K08 AI118538","107752/Z/15/Z","K24HL166024"],"pubmed_authors":["Hanekom WA","Olivier S","Reynolds Z","Pillay D","Gareta D","O'Cleirigh C","Ndung'u T","Siedner MJ","Wong EB","Modise TH","Khoza T","Gunda R","Herbst K","Vukuzazi Study Team","Stanton AM","Dolotina B","Boyd RL","Koole O"],"additional_accession":[]},"is_claimable":false,"name":"HIV, multimorbidity, and health-related quality of life in rural KwaZulu-Natal, South Africa: A population-based study.","description":"Health-related quality of life (HRQoL) assesses the perceived impact of health status across life domains. Although research has explored the relationship between specific conditions, including HIV, and HRQoL in low-resource settings, less attention has been paid to the association between multimorbidity and HRQoL. In a secondary analysis of cross-sectional data from the Vukuzazi (\"Wake up and know ourselves\" in isiZulu) study, which identified the prevalence and overlap of non-communicable and infectious diseases in the uMkhanyakunde district of KwaZulu-Natal, we (1) evaluated the impact of multimorbidity on HRQoL; (2) determined the relative associations among infectious diseases, non-communicable diseases (NCDs), and HRQoL; and (3) examined the effects of controlled versus non-controlle","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024","modification":"2026-06-18T06:54:43.879Z","creation":"2025-04-06T22:47:12.757Z"},"accession":"S-EPMC10880982","cross_references":{"pubmed":["38381724"],"doi":["10.1371/journal.pone.0293963"]}}