biostudies-literatureUnknown11(2)Sharif NThe ongoing 2023 dengue outbreak is the worst ever case reported in Bangladesh. There is a lack of epidemiological studies on the outbreak. A 2-tailed <i>t</i> test was performed. Multivariable logistic regression analysis was conducted. We found about 277 801 cases and 1393 deaths from the 2023 dengue outbreak. About 52% of the cases were from outside of Dhaka. The male:female ratio was about 3:2. The highest frequency of cases was found among people aged 19-29 years (28.7%, 79 673 of 277 801; <i>P</i> = .001). The overall case fatality rate (CFR) was 0.5%. The highest CFR was found among children aged 0-10 years (12%). Fever (99%) was the most prevalent, followed by joint pain (86%). We found significantly higher odds of fatalities (adjusted odds ratio [aOR], 4.21; 95% CI, 3.93-4.74; <i>Open forum infectious diseasesofae066https://www.ebi.ac.uk/biostudies/studies/S-EPMC10883285biostudies-literatureThe Epidemiologic and Clinical Characteristics of the 2023 Dengue Outbreak in Bangladesh.PMC10883285Dey SKSharif NKhan AfalseThe Epidemiologic and Clinical Characteristics of the 2023 Dengue Outbreak in Bangladesh.The ongoing 2023 dengue outbreak is the worst ever case reported in Bangladesh. There is a lack of epidemiological studies on the outbreak. A 2-tailed <i>t</i> test was performed. Multivariable logistic regression analysis was conducted. We found about 277 801 cases and 1393 deaths from the 2023 dengue outbreak. About 52% of the cases were from outside of Dhaka. The male:female ratio was about 3:2. The highest frequency of cases was found among people aged 19-29 years (28.7%, 79 673 of 277 801; <i>P</i> = .001). The overall case fatality rate (CFR) was 0.5%. The highest CFR was found among children aged 0-10 years (12%). Fever (99%) was the most prevalent, followed by joint pain (86%). We found significantly higher odds of fatalities (adjusted odds ratio [aOR], 4.21; 95% CI, 3.93-4.74; <i>2024-01-01T00:00:00Z2024 Feb2025-04-18T16:09:23.741Z2025-04-07T03:12:38.725ZS-EPMC108832853839046010.1093/ofid/ofae066