biostudies-literatureUnknown15Xu SRice sheath blight is a fungal disease caused mainly by <i>Rhizoctonia solani</i> AG1-IA. Toxins are a major pathogenic factor of <i>R. solani</i>, and some studies have reported their toxin components; however, there is no unified conclusion. In this study, we reported the toxin components and their targets that play a role in <i>R. solani</i> AG1-IA. First, toxins produced by <i>R. solani</i> AG1-IA were examined. Several important phytotoxins, including benzoic acid (BZA), 5-hydroxymethyl-2-furanic aid (HFA), and catechol (CAT), were identified by comparative analysis of secondary metabolites from AG1-IA, AG1-IB, and healthy rice. Follow-up studies have shown that the toxin components of this fungus can rapidly disintegrate the biofilm structure while maintaining the content of host plaFrontiers in plant science1348257https://www.ebi.ac.uk/biostudies/studies/S-EPMC10896845biostudies-literatureIdentification of the toxin components of <i>Rhizoctonia solani</i> AG1-IA and its destructive effect on plant cell membrane structure.PMC10896845Li WLi XYang GDong WYu BLi CZhang YBao WXu SRen SfalseIdentification of the toxin components of <i>Rhizoctonia solani</i> AG1-IA and its destructive effect on plant cell membrane structure.Rice sheath blight is a fungal disease caused mainly by <i>Rhizoctonia solani</i> AG1-IA. Toxins are a major pathogenic factor of <i>R. solani</i>, and some studies have reported their toxin components; however, there is no unified conclusion. In this study, we reported the toxin components and their targets that play a role in <i>R. solani</i> AG1-IA. First, toxins produced by <i>R. solani</i> AG1-IA were examined. Several important phytotoxins, including benzoic acid (BZA), 5-hydroxymethyl-2-furanic aid (HFA), and catechol (CAT), were identified by comparative analysis of secondary metabolites from AG1-IA, AG1-IB, and healthy rice. Follow-up studies have shown that the toxin components of this fungus can rapidly disintegrate the biofilm structure while maintaining the content of host pla2024-01-01T00:00:00Z20242025-05-29T20:26:58.839Z2025-05-29T20:26:58.839ZS-EPMC108968453841464410.3389/fpls.2024.1348257