biostudies-literatureUnknown15Thaysen-Petersen D<h4>Introduction</h4>Cognitive behavioral therapy (CBT) is an evidence-based treatment for alcohol use disorder (AUD). Exposure to high-risk situations in virtual reality (VR) has been suggested to have a potential therapeutical benefit, but no previous study has combined VR and CBT for AUD. We aimed to investigate the feasibility of using VR-simulated high-risk environments in CBT-based treatment of AUD.<h4>Methods</h4>We randomized ten treatment-seeking AUD-diagnosed individuals to three sessions of conventional CBT or VR-assisted CBT performed at two outpatient clinics in Denmark. In each session, patients randomized to VR-CBT were exposed to VR-simulations from a restaurant to induce authentic thoughts, emotions, physiological reactions, and craving for CBT purposes. The primary outcomFrontiers in psychiatry1337898https://www.ebi.ac.uk/biostudies/studies/S-EPMC10899342biostudies-literatureVirtual reality-assisted cognitive behavioral therapy for patients with alcohol use disorder: a randomized feasibility study.PMC10899342Hammerum SKThaysen-Petersen DFink-Jensen ADuring SWOestrich IHVissing ACNordentoft MfalseVirtual reality-assisted cognitive behavioral therapy for patients with alcohol use disorder: a randomized feasibility study.<h4>Introduction</h4>Cognitive behavioral therapy (CBT) is an evidence-based treatment for alcohol use disorder (AUD). Exposure to high-risk situations in virtual reality (VR) has been suggested to have a potential therapeutical benefit, but no previous study has combined VR and CBT for AUD. We aimed to investigate the feasibility of using VR-simulated high-risk environments in CBT-based treatment of AUD.<h4>Methods</h4>We randomized ten treatment-seeking AUD-diagnosed individuals to three sessions of conventional CBT or VR-assisted CBT performed at two outpatient clinics in Denmark. In each session, patients randomized to VR-CBT were exposed to VR-simulations from a restaurant to induce authentic thoughts, emotions, physiological reactions, and craving for CBT purposes. The primary outcom2024-01-01T00:00:00Z20242026-06-01T19:55:52.044Z2025-02-19T01:42:07.014ZS-EPMC108993423841990510.3389/fpsyt.2024.1337898