{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Ma Y"],"funding":["NCATS NIH HHS","NIA NIH HHS","NIDA NIH HHS","U.S. Department of Health &amp; Human Services | NIH | National Institute on Aging","NIMHD NIH HHS","U.S. Department of Health &amp; Human Services | NIH | National Institute on Minority Health and Health Disparities","NIH HHS","U.S. Department of Health &amp; Human Services | National Institutes of Health"],"pagination":["2074-2083"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10901568"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["7(12)"],"pubmed_abstract":["Average ambient fine particulate matter (PM<sub>2.5</sub>) concentrations have decreased in the US in recent years, but the health benefits of this improvement among different racial/ethnic groups are unknown. We estimate the associations between long-term exposure to ambient PM<sub>2.5</sub> and cause-specific cardiovascular disease (CVD) mortality rate and assess the PM<sub>2.5</sub>-attributable CVD deaths by race/ethnicity across 3,103 US counties during 2001-2016 (n = 595,776 county-months). A 1 µg m<sup>-</sup><sup>3</sup> increase in PM<sub>2.5</sub> concentration was associated with increases of 7.16 (95% confidence interval (CI): 3.81, 10.51) CVD deaths per 1,000,000 Black people per month, significantly higher than the estimates for non-Hispanic white people (1.76 (95% CI: 1.37, 2.15); difference in coefficients: 5.40 (95% CI: 2.03, 8.77), P = 0.001). No significant difference in this association was observed between Hispanic (2.66 (95% CI: -0.03, 5.35)) and non-Hispanic white people (difference in coefficients: 0.90 (95% CI: -1.81, 3.61), P = 0.523). From 2001 to 2016, the absolute disparity in PM<sub>2.5</sub>-attributable CVD mortality burden was reduced by 44.04% between non-Hispanic Black and white people and by 2.61% between Hispanic and non-Hispanic white people. However, in 2016, the burden remained 3.47 times higher for non-Hispanic Black people and 0.45 times higher for Hispanic people than for non-Hispanic white people. We call for policies that aim to reduce both exposure and vulnerability to PM<sub>2.5</sub> for racial/ethnic minorities."],"journal":["Nature human behaviour"],"pubmed_title":["Racial/ethnic disparities in PM&lt;sub&gt;2.5&lt;/sub&gt;-attributable cardiovascular mortality burden in the United States."],"pmcid":["PMC10901568"],"funding_grant_id":["P30AG021342","R21 AG074238","R01MD016054","R01 MD017298","R01 MD016054","DP5OD029636","P30 AG021342","L60 DA054692","R21AG074238-01","UL1 TR001863","DP5 OD029636","DP1 DA058982"],"pubmed_authors":["Chen K","Lu Y","Krumholz HM","Ma Y","Zang E","Opara I"],"additional_accession":[]},"is_claimable":false,"name":"Racial/ethnic disparities in PM&lt;sub&gt;2.5&lt;/sub&gt;-attributable cardiovascular mortality burden in the United States.","description":"Average ambient fine particulate matter (PM<sub>2.5</sub>) concentrations have decreased in the US in recent years, but the health benefits of this improvement among different racial/ethnic groups are unknown. We estimate the associations between long-term exposure to ambient PM<sub>2.5</sub> and cause-specific cardiovascular disease (CVD) mortality rate and assess the PM<sub>2.5</sub>-attributable CVD deaths by race/ethnicity across 3,103 US counties during 2001-2016 (n = 595,776 county-months). A 1 µg m<sup>-</sup><sup>3</sup> increase in PM<sub>2.5</sub> concentration was associated with increases of 7.16 (95% confidence interval (CI): 3.81, 10.51) CVD deaths per 1,000,000 Black people per month, significantly higher than the estimates for non-Hispanic white people (1.76 (95% CI: 1.37, 2.15); difference in coefficients: 5.40 (95% CI: 2.03, 8.77), P = 0.001). No significant difference in this association was observed between Hispanic (2.66 (95% CI: -0.03, 5.35)) and non-Hispanic white people (difference in coefficients: 0.90 (95% CI: -1.81, 3.61), P = 0.523). From 2001 to 2016, the absolute disparity in PM<sub>2.5</sub>-attributable CVD mortality burden was reduced by 44.04% between non-Hispanic Black and white people and by 2.61% between Hispanic and non-Hispanic white people. However, in 2016, the burden remained 3.47 times higher for non-Hispanic Black people and 0.45 times higher for Hispanic people than for non-Hispanic white people. We call for policies that aim to reduce both exposure and vulnerability to PM<sub>2.5</sub> for racial/ethnic minorities.","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Dec","modification":"2025-04-19T16:11:36.583Z","creation":"2025-04-19T16:11:36.583Z"},"accession":"S-EPMC10901568","cross_references":{"pubmed":["37653149"],"doi":["10.1038/s41562-023-01694-7"]}}