biostudies-literatureVicente MHMinas Gerais State Research Support FoundationNational Institute of Science and Technology in Plant PhysiologyCoordination of Superior Level Staff Improvement (CAPES, Brazil)/Alexander von Humboldt Foundationthe Global Challenges Research FundNational Council for Scientific and Technological DevelopmentMajor Special Projects and Key R&amp;D Projects in Yunnan Provincethe São Paulo State Research Support FoundationBiotechnology and Biological Sciences Research CouncilRoyal Society’s Newton Mobility1233-1248https://www.ebi.ac.uk/biostudies/studies/S-EPMC10902882biostudies-literatureUnknown132(7)<h4>Background and aims</h4>Gigantism is a key component of the domestication syndrome, a suite of traits that differentiates crops from their wild relatives. Allometric gigantism is strongly marked in horticultural crops, causing disproportionate increases in the size of edible parts such as stems, leaves or fruits. Tomato (Solanum lycopersicum) has attracted attention as a model for fruit gigantism, and many genes have been described controlling this trait. However, the genetic basis of a corresponding increase in size of vegetative organs contributing to isometric gigantism has remained relatively unexplored.<h4>Methods</h4>Here, we identified a 0.4-Mb region on chromosome 7 in introgression lines (ILs) from the wild species Solanum pennellii in two different tomato genetic backgrounds Annals of botanyThe ORGAN SIZE (ORG) locus modulates both vegetative and reproductive gigantism in domesticated tomato.PMC10902882FAPESP, Brazil, 2018/050003-116/05566-0 to M.H.V.202102AE090020202102AE090054INCT, Plant Stress Physiology, 406455/2022-8FAPEMIG, Brazil, APQ-01942-22 to A.Z.88881.472837/2019-01 to A.Z.BB/S007970/1NMG\R2\170027306518/2018-0Mohareb FKevei ZFernie ARThompson AJZhu FMacLeod KFigueira AVicente MHZsogon ARafael DDPeres LEPfalseThe ORGAN SIZE (ORG) locus modulates both vegetative and reproductive gigantism in domesticated tomato.<h4>Background and aims</h4>Gigantism is a key component of the domestication syndrome, a suite of traits that differentiates crops from their wild relatives. Allometric gigantism is strongly marked in horticultural crops, causing disproportionate increases in the size of edible parts such as stems, leaves or fruits. Tomato (Solanum lycopersicum) has attracted attention as a model for fruit gigantism, and many genes have been described controlling this trait. However, the genetic basis of a corresponding increase in size of vegetative organs contributing to isometric gigantism has remained relatively unexplored.<h4>Methods</h4>Here, we identified a 0.4-Mb region on chromosome 7 in introgression lines (ILs) from the wild species Solanum pennellii in two different tomato genetic backgrounds 2023-01-01T00:00:00Z2023 Dec2026-07-14T19:44:56.166Z2025-04-04T02:05:10.639ZS-EPMC109028823781889310.1093/aob/mcad150