{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10(5)"],"submitter":["Xiao L"],"funding":["Natural Science Foundation of Guangdong Province"],"pubmed_abstract":["<h4>Backgrounds</h4>Global fertility rates continue to decline and sperm quality is a prime factor affecting male fertility. Both extreme cold and heat have been demonstrated to be associated with decreased sperm quality, but no epidemiological studies have considered human adaptation to long-term temperature. Our aim was to conduct a multi-center retrospective cohort study to investigate exposure-response relationship between temperature anomaly (TA) that deviate from long-term climate patterns and sperm quality.<h4>Methods</h4>A total of 78,952 semen samples measured in 33,234 donors from 6 provincial human sperm banks in China were collected. This study considered heat and cold acclimatization to prolonged exposure in humans and explored the exposure-response relationship between TAs an"],"journal":["Heliyon"],"pagination":["e26765"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10907732"],"repository":["biostudies-literature"],"pubmed_title":["Effects of temperature anomaly on sperm quality: A multi-center study of 33,234 men."],"pmcid":["PMC10907732"],"pubmed_authors":["Meng T","Zeng Q","Ni H","Li F","Song C","Dai T","Guo P","Wang L","Sheng H","Li Y","Xiao L","Wang Q","Zhang X","Xu T","Cai X","Yu X"],"additional_accession":[]},"is_claimable":false,"name":"Effects of temperature anomaly on sperm quality: A multi-center study of 33,234 men.","description":"<h4>Backgrounds</h4>Global fertility rates continue to decline and sperm quality is a prime factor affecting male fertility. Both extreme cold and heat have been demonstrated to be associated with decreased sperm quality, but no epidemiological studies have considered human adaptation to long-term temperature. Our aim was to conduct a multi-center retrospective cohort study to investigate exposure-response relationship between temperature anomaly (TA) that deviate from long-term climate patterns and sperm quality.<h4>Methods</h4>A total of 78,952 semen samples measured in 33,234 donors from 6 provincial human sperm banks in China were collected. This study considered heat and cold acclimatization to prolonged exposure in humans and explored the exposure-response relationship between TAs an","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Mar","modification":"2026-06-12T05:48:38.977Z","creation":"2025-04-05T11:38:52.326Z"},"accession":"S-EPMC10907732","cross_references":{"pubmed":["38434420"],"doi":["10.1016/j.heliyon.2024.e26765"]}}