biostudies-literatureUnknown10Julius LANDielectrophoresis is a powerful and well-established technique that allows label-free, non-invasive manipulation of cells and particles by leveraging their electrical properties. The practical implementation of the associated electronics and user interface in a biology laboratory, however, requires an engineering background, thus hindering the broader adoption of the technique. In order to address these challenges and to bridge the gap between biologists and the engineering skills required for the implementation of DEP platforms, we report here a custom-built, compact, universal electronic platform termed ADEPT (adaptable dielectrophoresis embedded platform tool) for use with a simple microfluidic chip containing six microelectrodes. The versatility of the open-source platform is ensured bMicrosystems & nanoengineering29https://www.ebi.ac.uk/biostudies/studies/S-EPMC10907756biostudies-literaturePortable dielectrophoresis for biology: ADEPT facilitates cell trapping, separation, and interactions.PMC10907756Krishnan GKorvink JAkgul DJulius LANFalk FBadilita VfalsePortable dielectrophoresis for biology: ADEPT facilitates cell trapping, separation, and interactions.Dielectrophoresis is a powerful and well-established technique that allows label-free, non-invasive manipulation of cells and particles by leveraging their electrical properties. The practical implementation of the associated electronics and user interface in a biology laboratory, however, requires an engineering background, thus hindering the broader adoption of the technique. In order to address these challenges and to bridge the gap between biologists and the engineering skills required for the implementation of DEP platforms, we report here a custom-built, compact, universal electronic platform termed ADEPT (adaptable dielectrophoresis embedded platform tool) for use with a simple microfluidic chip containing six microelectrodes. The versatility of the open-source platform is ensured b2024-01-01T00:00:00Z20242025-04-18T17:14:51.227Z2024-11-13T17:04:59.22ZS-EPMC109077563843458710.1038/s41378-024-00654-z