biostudies-literatureShaw DNational Institute for Health Research (NIHR)University of OxfordWellcome Truste582-e593https://www.ebi.ac.uk/biostudies/studies/S-EPMC10914672biostudies-literatureUnknown5(9)<h4>Background</h4>The Invasive Respiratory Infection Surveillance (IRIS) Consortium was established to assess the impact of the COVID-19 pandemic on invasive diseases caused by Streptococcus pneumoniae, Haemophilus influenzae, Neisseria meningitidis, and Streptococcus agalactiae. We aimed to analyse the incidence and distribution of these diseases during the first 2 years of the COVID-19 pandemic compared to the 2 years preceding the pandemic.<h4>Methods</h4>For this prospective analysis, laboratories in 30 countries and territories representing five continents submitted surveillance data from Jan 1, 2018, to Jan 2, 2022, to private projects within databases in PubMLST. The impact of COVID-19 containment measures on the overall number of cases was analysed, and changes in disease distribuThe Lancet. Digital healthTrends in invasive bacterial diseases during the first 2 years of the COVID-19 pandemic: analyses of prospective surveillance data from 30 countries and territories in the IRIS Consortium.PMC10914672203141/Z/16/Z206394/C/17/Z218205206394218205/Z/19/Z206394/Z/17/ZSiira LCuypers LCasanova COftadeh SSintchenko VMeiring SSloan MLam TTDeghmane AEMartin IPerez-Vazquez MCoelho JJolley KAClaus HMeehan MMzabi ARon MAbad RKristinsson KGFuursted KHumphreys Hvan der Linden MPGHenriques-Normark Bvan Sorge NMJohnston JDavies HMcCarthy NDNovakova LHoffmann SChoi EHFry NKKozakova JLadhani SShaw DHilty MKuch ACao BSmith AJDesmet STaha MKKrizova PMusilek MZhou FSkoczynska ATzanakaki GHale Tdu Plessis MCorcoran MScott KJDrew RMulhall RLitt DDalby TSteens ARoberts MToropainen MLeon MEAmin-Chowdhury ZSanabria OMMurdoch DMolling PLindholm LPrevost BVaron EPerrin MIp MBroughton KMattheus WZanella RDomenech MRokney ACunney RVohrnova SYuste JSlotved HCMartiny DVainio AJacobsson SMaiden MCJHenares DErlendsdottir HMurphy Jvon Gottberg ADemczuk WJohnson CMorgan JPerez-Arguello ABrueggemann ABBennett DBautista AChu YWMorfeldt EKawabata AMunoz-Almagro CCottrell SPerry MDuarte Cde Gouveia LSheppard CfalseTrends in invasive bacterial diseases during the first 2 years of the COVID-19 pandemic: analyses of prospective surveillance data from 30 countries and territories in the IRIS Consortium.<h4>Background</h4>The Invasive Respiratory Infection Surveillance (IRIS) Consortium was established to assess the impact of the COVID-19 pandemic on invasive diseases caused by Streptococcus pneumoniae, Haemophilus influenzae, Neisseria meningitidis, and Streptococcus agalactiae. We aimed to analyse the incidence and distribution of these diseases during the first 2 years of the COVID-19 pandemic compared to the 2 years preceding the pandemic.<h4>Methods</h4>For this prospective analysis, laboratories in 30 countries and territories representing five continents submitted surveillance data from Jan 1, 2018, to Jan 2, 2022, to private projects within databases in PubMLST. The impact of COVID-19 containment measures on the overall number of cases was analysed, and changes in disease distribu2023-01-01T00:00:00Z2023 Sep2026-06-09T07:00:06.733Z2026-06-09T03:12:07.076ZS-EPMC109146723751655710.1016/S2589-7500(23)00108-5