{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["14(1)"],"submitter":["Hamal EK"],"pubmed_abstract":["In the quest for alternative renewable energy sources, a new self-assembled hybrid configuration of cellulose-coated oil-in-water emulsion particles with yeast was formed. In this research, the addition of yeasts (S. cerevisiae) to the micro-particle emulsion revealed a novel self-assembly configuration in which the yeast cell is connected to surrounding cellulose-coated micro-particles. This hybrid configuration may enhance the simultaneous saccharification and fermentation process by substrate channeling. Glucose produced by hydrolysis of the cellulose shells coating the micro-particles, catalyzed by cellulytic enzymes attached to their coating, is directly fermented to ethanol by the yeasts to which the particles are connected. The results indicate ethanol yield of 62%, based on the cellulose content of the emulsion, achieved by the yeast/micro-particle hybrids. The functionality of this hybrid configuration is expected to serve as a micro-reactor for a cascade of biochemical reactions in a \"one-pot\" consolidated process transforming cellulose to valuable chemicals, such as biodiesel."],"journal":["Scientific reports"],"pagination":["5499"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10918086"],"repository":["biostudies-literature"],"pubmed_title":["Cellulose-coated emulsion micro-particles self-assemble with yeasts for cellulose bio-conversion."],"pmcid":["PMC10918086"],"pubmed_authors":["Alfassi G","Rein DM","Cohen Y","Antonenko M","Hamal EK"],"additional_accession":[]},"is_claimable":false,"name":"Cellulose-coated emulsion micro-particles self-assemble with yeasts for cellulose bio-conversion.","description":"In the quest for alternative renewable energy sources, a new self-assembled hybrid configuration of cellulose-coated oil-in-water emulsion particles with yeast was formed. In this research, the addition of yeasts (S. cerevisiae) to the micro-particle emulsion revealed a novel self-assembly configuration in which the yeast cell is connected to surrounding cellulose-coated micro-particles. This hybrid configuration may enhance the simultaneous saccharification and fermentation process by substrate channeling. Glucose produced by hydrolysis of the cellulose shells coating the micro-particles, catalyzed by cellulytic enzymes attached to their coating, is directly fermented to ethanol by the yeasts to which the particles are connected. The results indicate ethanol yield of 62%, based on the cellulose content of the emulsion, achieved by the yeast/micro-particle hybrids. The functionality of this hybrid configuration is expected to serve as a micro-reactor for a cascade of biochemical reactions in a \"one-pot\" consolidated process transforming cellulose to valuable chemicals, such as biodiesel.","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Mar","modification":"2025-04-04T12:35:01.602Z","creation":"2025-04-04T12:35:01.602Z"},"accession":"S-EPMC10918086","cross_references":{"pubmed":["38448579"],"doi":["10.1038/s41598-024-56204-0"]}}