{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9(9)"],"submitter":["Salem ME"],"pubmed_abstract":["A series of novel thieno[2,3-<i>b</i>]pyridines linked to <i>N</i>-aryl carboxamides or (carbonylphenoxy)-<i>N</i>-(aryl)acetamides, as well as bis(thieno[2,3-<i>b</i>]pyridines) linked to piperazine core via methanone or carbonylphenoxyethanone units, were synthesized by treating the appropriate chloroacetyl- or bis-bromoacetyl derivatives with 2-mercaptonicotinonitrile derivatives in ethanolic sodium ethoxide at reflux. The spectral data were used to determine the compositions of novel compounds."],"journal":["ACS omega"],"pagination":["10146-10159"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10918660"],"repository":["biostudies-literature"],"pubmed_title":["Utility of 2-Chloro-<i>N</i>-arylacetamide and 1,1'-(Piperazine-1,4-diyl)bis(2-chloroethanone) as Versatile Precursors for Novel Mono- and Bis[thienopyridines]."],"pmcid":["PMC10918660"],"pubmed_authors":["Abdelhamid IA","Salem ME","Abdullah AH","Zaki MEA","Elwahy AHM"],"additional_accession":[]},"is_claimable":false,"name":"Utility of 2-Chloro-<i>N</i>-arylacetamide and 1,1'-(Piperazine-1,4-diyl)bis(2-chloroethanone) as Versatile Precursors for Novel Mono- and Bis[thienopyridines].","description":"A series of novel thieno[2,3-<i>b</i>]pyridines linked to <i>N</i>-aryl carboxamides or (carbonylphenoxy)-<i>N</i>-(aryl)acetamides, as well as bis(thieno[2,3-<i>b</i>]pyridines) linked to piperazine core via methanone or carbonylphenoxyethanone units, were synthesized by treating the appropriate chloroacetyl- or bis-bromoacetyl derivatives with 2-mercaptonicotinonitrile derivatives in ethanolic sodium ethoxide at reflux. The spectral data were used to determine the compositions of novel compounds.","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Mar","modification":"2025-04-04T12:58:28.189Z","creation":"2025-04-04T12:58:28.189Z"},"accession":"S-EPMC10918660","cross_references":{"pubmed":["38463260"],"doi":["10.1021/acsomega.3c06653"]}}