<HashMap><database>biostudies-literature</database><scores/><additional><submitter>Pool M</submitter><funding>Medical Research Council</funding><funding>South African Medical Research Council</funding><pagination>e0299584</pagination><full_dataset_link>https://www.ebi.ac.uk/biostudies/studies/S-EPMC10919616</full_dataset_link><repository>biostudies-literature</repository><omics_type>Unknown</omics_type><volume>19(3)</volume><pubmed_abstract>&lt;h4>Introduction&lt;/h4>Healthcare workers globally have experienced increased social and occupational stressors in their working environments and communities because of COVID-19 which has increased the risk of mental health concerns. This study aimed to explore the prevalence and correlates of depression and anxiety amongst healthcare workers during the COVID-19 pandemic in the Western Cape, South Africa. In addition, role-related stressors and coping strategies were explored.&lt;h4>Material and methods&lt;/h4>We conducted a cross-sectional survey of doctors and nurses working in public healthcare facilities across the Western Cape, South Africa. Participants completed the Generalized Anxiety Disorder-7 (GAD-7), the Center for Epidemiologic Studies Depression (CES-D), the Professional Quality of Life (PROQL-R-IV), and the Brief Coping Orientation to Problems Experienced (COPE-R) scales. Data were analysed using multivariable logistic regression analysis.&lt;h4>Results&lt;/h4>The sample comprised 416 health workers (303 nurses, 113 doctors). Almost 40% of the sample (n = 161) had CES-D scores suggestive of probable depression, and 45.9% (n = 186) had GAD-7 scores suggestive of anxiety. In the logistic regression model, the odds of probable depression were higher for female participants compared to men (OR = 2.26, 95% CI 1.00-5.10) and for participants who used behavioural disengagement as a coping strategy (OR = 1.50, 95% CI 1.14-1.97). More time spent working with COVID patients was associated with increased odds of having high levels of anxiety [OR = 1.13, 95% CI (1.02-1.25). Substance use (OR = 1.39, 95% CI 1.08-1.81), venting (OR = 1.31, 95% CI 1.01-1.70), and self-blame (OR = 1.42, 95% CI 1.08-1.87) were some of the coping strategies used by healthcare workers. High levels of secondary traumatic stress and burnout were found to increase the odds of both depression and anxiety.&lt;h4>Conclusion&lt;/h4>Findings of this study suggest that there is a high prevalence of mental health issues among healthcare workers, and a critical need to focus on workplace mental health interventions to support these frontline workers.</pubmed_abstract><journal>PloS one</journal><pubmed_title>The prevalence of and factors associated with depressive and anxiety symptoms during the COVID-19 pandemic among healthcare workers in South Africa.</pubmed_title><pmcid>PMC10919616</pmcid><funding_grant_id>MR/M014290/1</funding_grant_id><funding_grant_id>(BM-NHSP)</funding_grant_id><pubmed_authors>Sorsdahl K</pubmed_authors><pubmed_authors>Myers B</pubmed_authors><pubmed_authors>van der Westhuizen C</pubmed_authors><pubmed_authors>Pool M</pubmed_authors></additional><is_claimable>false</is_claimable><name>The prevalence of and factors associated with depressive and anxiety symptoms during the COVID-19 pandemic among healthcare workers in South Africa.</name><description>&lt;h4>Introduction&lt;/h4>Healthcare workers globally have experienced increased social and occupational stressors in their working environments and communities because of COVID-19 which has increased the risk of mental health concerns. This study aimed to explore the prevalence and correlates of depression and anxiety amongst healthcare workers during the COVID-19 pandemic in the Western Cape, South Africa. In addition, role-related stressors and coping strategies were explored.&lt;h4>Material and methods&lt;/h4>We conducted a cross-sectional survey of doctors and nurses working in public healthcare facilities across the Western Cape, South Africa. Participants completed the Generalized Anxiety Disorder-7 (GAD-7), the Center for Epidemiologic Studies Depression (CES-D), the Professional Quality of Life (PROQL-R-IV), and the Brief Coping Orientation to Problems Experienced (COPE-R) scales. Data were analysed using multivariable logistic regression analysis.&lt;h4>Results&lt;/h4>The sample comprised 416 health workers (303 nurses, 113 doctors). Almost 40% of the sample (n = 161) had CES-D scores suggestive of probable depression, and 45.9% (n = 186) had GAD-7 scores suggestive of anxiety. In the logistic regression model, the odds of probable depression were higher for female participants compared to men (OR = 2.26, 95% CI 1.00-5.10) and for participants who used behavioural disengagement as a coping strategy (OR = 1.50, 95% CI 1.14-1.97). More time spent working with COVID patients was associated with increased odds of having high levels of anxiety [OR = 1.13, 95% CI (1.02-1.25). Substance use (OR = 1.39, 95% CI 1.08-1.81), venting (OR = 1.31, 95% CI 1.01-1.70), and self-blame (OR = 1.42, 95% CI 1.08-1.87) were some of the coping strategies used by healthcare workers. High levels of secondary traumatic stress and burnout were found to increase the odds of both depression and anxiety.&lt;h4>Conclusion&lt;/h4>Findings of this study suggest that there is a high prevalence of mental health issues among healthcare workers, and a critical need to focus on workplace mental health interventions to support these frontline workers.</description><dates><release>2024-01-01T00:00:00Z</release><publication>2024</publication><modification>2026-06-12T10:07:26.906Z</modification><creation>2025-04-04T12:34:47.352Z</creation></dates><accession>S-EPMC10919616</accession><cross_references><pubmed>38451982</pubmed><doi>10.1371/journal.pone.0299584</doi></cross_references></HashMap>