{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Fang L"],"funding":["National Natural Science Foundation of China"],"pagination":["79"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10921815"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["24(1)"],"pubmed_abstract":["<h4>Objective</h4>To explore the changes and potential mechanisms of microbiome in different parts of the upper airway in the development of pediatric OSA and observe the impact of surgical intervention on oral microbiome for pediatric OSA.<h4>Methods</h4>Before adeno-tonsillectomy, we collected throat swab samples from different parts of the oropharynx and nasopharynx of 30 OSA patients and 10 non-OSA patients and collected throat swab samples from the oropharynx of the above patients one month after the adeno-tonsillectomy. The 16 S rRNA V3-V4 region was sequenced to identify the microbial communities. The correlation analysis was conducted based on clinical characteristics.<h4>Results</h4>There was a significant difference of alpha diversity in different parts of the upper airway of ped"],"journal":["BMC microbiology"],"pubmed_title":["Changes in the nasopharyngeal and oropharyngeal microbiota in pediatric obstructive sleep apnea before and after surgery: a prospective study."],"pmcid":["PMC10921815"],"funding_grant_id":["82071033"],"pubmed_authors":["Tuohuti A","Chen X","Fang L","Cai W"],"additional_accession":[]},"is_claimable":false,"name":"Changes in the nasopharyngeal and oropharyngeal microbiota in pediatric obstructive sleep apnea before and after surgery: a prospective study.","description":"<h4>Objective</h4>To explore the changes and potential mechanisms of microbiome in different parts of the upper airway in the development of pediatric OSA and observe the impact of surgical intervention on oral microbiome for pediatric OSA.<h4>Methods</h4>Before adeno-tonsillectomy, we collected throat swab samples from different parts of the oropharynx and nasopharynx of 30 OSA patients and 10 non-OSA patients and collected throat swab samples from the oropharynx of the above patients one month after the adeno-tonsillectomy. The 16 S rRNA V3-V4 region was sequenced to identify the microbial communities. The correlation analysis was conducted based on clinical characteristics.<h4>Results</h4>There was a significant difference of alpha diversity in different parts of the upper airway of ped","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Mar","modification":"2026-07-15T14:02:46.529Z","creation":"2026-07-06T03:09:01.045Z"},"accession":"S-EPMC10921815","cross_references":{"pubmed":["38459431"],"doi":["10.1186/s12866-024-03230-7"]}}