{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Arnold EM"],"funding":["NCATS NIH HHS","NICHD NIH HHS","NIAID NIH HHS","NIMH NIH HHS","National Institute of Child Health and Human Development"],"pagination":["215-221"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10922292"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["95(3)"],"pubmed_abstract":["<h4>Background</h4>Youth living with HIV (YLH) have an increased risk for psychosocial stressors that can affect their antiretroviral (ARV) adherence. We examined factors associated with self-reported ARV adherence among YLH ages 12-24 years old.<h4>Setting</h4>YLH (N = 147) were recruited in Los Angeles, CA, and New Orleans, LA from 2017 to 2020.<h4>Methods</h4>YLH whose self-reported recent (30 days) ARV adherence was \"excellent\" or \"very good\" were compared with nonadherent YLH on sociodemographic, clinical, and psychosocial factors using univariate and multivariate analyses.<h4>Results</h4>Participants were predominantly male (88%), and 81% identified as gay, bisexual, transgender, queer, or other. The mean duration on ARV was 27 months (range 0-237 months). Most YLH (71.2%) self-reported being adherent, and 79% of those who self-reported adherence were also virally suppressed (<200 copies/mL). Multivariate analysis indicated being adherent was significantly associated with white race [aOR = 8.07, confidence intervals (CI): 1.45 to 74.0], Hispanic/Latinx ethnicity [aOR = 3.57, CI: 1.16 to 12.80], more social support [aOR = 1.11, CI: 1.05 to 1.18], and being on ARV for a shorter duration [aOR = 0.99, CI: 0.97 to 0.99]. Mental health symptoms, substance use, age, and history of homelessness or incarceration were unrelated to adherence.<h4>Conclusions</h4>Enhancing efforts to provide support for adherence to non-white youth, and those with limited social support and who have been on ARV treatment longer, may help increase viral suppression among YLH."],"journal":["Journal of acquired immune deficiency syndromes (1999)"],"pubmed_title":["Factors Associated With Antiretroviral Adherence Among Youth Living With HIV."],"pmcid":["PMC10922292"],"funding_grant_id":["U19HD089886","P30 AI028697","UL1 TR000124","UL1 TR001881","U19 HD089886","P30 MH058107"],"pubmed_authors":["Swendeman D","Kamal S","Rotheram-Borus MJ","Gertsch W","Arnold EM","Bridges SK","Norwood P","Adolescent Medicine Trials Network (ATN) CARES Team"],"additional_accession":[]},"is_claimable":false,"name":"Factors Associated With Antiretroviral Adherence Among Youth Living With HIV.","description":"<h4>Background</h4>Youth living with HIV (YLH) have an increased risk for psychosocial stressors that can affect their antiretroviral (ARV) adherence. We examined factors associated with self-reported ARV adherence among YLH ages 12-24 years old.<h4>Setting</h4>YLH (N = 147) were recruited in Los Angeles, CA, and New Orleans, LA from 2017 to 2020.<h4>Methods</h4>YLH whose self-reported recent (30 days) ARV adherence was \"excellent\" or \"very good\" were compared with nonadherent YLH on sociodemographic, clinical, and psychosocial factors using univariate and multivariate analyses.<h4>Results</h4>Participants were predominantly male (88%), and 81% identified as gay, bisexual, transgender, queer, or other. The mean duration on ARV was 27 months (range 0-237 months). Most YLH (71.2%) self-reported being adherent, and 79% of those who self-reported adherence were also virally suppressed (<200 copies/mL). Multivariate analysis indicated being adherent was significantly associated with white race [aOR = 8.07, confidence intervals (CI): 1.45 to 74.0], Hispanic/Latinx ethnicity [aOR = 3.57, CI: 1.16 to 12.80], more social support [aOR = 1.11, CI: 1.05 to 1.18], and being on ARV for a shorter duration [aOR = 0.99, CI: 0.97 to 0.99]. Mental health symptoms, substance use, age, and history of homelessness or incarceration were unrelated to adherence.<h4>Conclusions</h4>Enhancing efforts to provide support for adherence to non-white youth, and those with limited social support and who have been on ARV treatment longer, may help increase viral suppression among YLH.","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Mar","modification":"2026-06-01T08:52:13.491Z","creation":"2025-04-07T11:28:36.84Z"},"accession":"S-EPMC10922292","cross_references":{"pubmed":["37977178"],"doi":["10.1097/qai.0000000000003345","10.1097/QAI.0000000000003345"]}}