biostudies-literatureLe TPNIMH NIH HHSNational Institute of Mental HealthNational Institutes of Health149-155https://www.ebi.ac.uk/biostudies/studies/S-EPMC10923523biostudies-literatureUnknown262Schizophrenia is associated with a heavy economic burden in the United States that is partly due to the high rates of chronic unemployment. Individual Placement and Support (IPS) is an evidenced-based type of supported employment that can improve job obtainment and work outcomes in psychotic disorders. Outcomes vary widely and a persistent challenge for IPS is low levels of engagement in the initial job search phase. Past studies have focused on interview-based motivation deficits as a key determinant of poor treatment engagement and work outcomes in schizophrenia. New validated performance-based measures of motivation, including effort-based decision-making (EBDM) tasks, may explain supported employment outcomes and provide insights into individual differences in IPS outcomes. This study Schizophrenia researchEffort-based decision-making as a determinant of supported employment outcomes in psychotic disorders.PMC10923523T32 MH122395R21 MH110753Iglesias JEGreen MFWynn JKFranco RLKopelowicz ALe TPKern RSfalseEffort-based decision-making as a determinant of supported employment outcomes in psychotic disorders.Schizophrenia is associated with a heavy economic burden in the United States that is partly due to the high rates of chronic unemployment. Individual Placement and Support (IPS) is an evidenced-based type of supported employment that can improve job obtainment and work outcomes in psychotic disorders. Outcomes vary widely and a persistent challenge for IPS is low levels of engagement in the initial job search phase. Past studies have focused on interview-based motivation deficits as a key determinant of poor treatment engagement and work outcomes in schizophrenia. New validated performance-based measures of motivation, including effort-based decision-making (EBDM) tasks, may explain supported employment outcomes and provide insights into individual differences in IPS outcomes. This study 2023-01-01T00:00:00Z2023 Dec2025-04-04T01:18:48.508Z2025-04-04T01:18:48.508ZS-EPMC109235233797941810.1016/j.schres.2023.11.003