{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["14(1)"],"submitter":["Vasilevska V"],"funding":["European Research Area Network (ERA-NET) NEURON “Translational Biomarkers in Brain Disorders”"],"pubmed_abstract":["The global impact of SARS-CoV-2 infection has raised concerns about secondary diseases beyond acute illness. This review explores the significance and potential underlying mechanisms of how SARS-CoV-2 infection might elicit an immune response targeting N-methyl-D-aspartate (NMDA) receptors, and its implications for autoimmune-driven neuropsychiatric manifestations. We identified 19 published case reports of NMDA receptor encephalitis associated with SARS-CoV-2 infection or vaccination by a systematic literature search. The significance of these reports was limited since it is not clear if a coincidental or causal relationship exists between SARS-CoV-2 infection or vaccination and manifestation of NMDA receptor encephalitis. The included studies were hampered by difficulties in establishing"],"journal":["Translational psychiatry"],"pagination":["139"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10923949"],"repository":["biostudies-literature"],"pubmed_title":["Possible temporal relationship between SARS-CoV-2 infection and anti-NMDA receptor encephalitis: a meta-analysis."],"pmcid":["PMC10923949"],"pubmed_authors":["Guest PC","Vasilevska V","Szardenings M","Steiner J","Benros ME"],"additional_accession":[]},"is_claimable":false,"name":"Possible temporal relationship between SARS-CoV-2 infection and anti-NMDA receptor encephalitis: a meta-analysis.","description":"The global impact of SARS-CoV-2 infection has raised concerns about secondary diseases beyond acute illness. This review explores the significance and potential underlying mechanisms of how SARS-CoV-2 infection might elicit an immune response targeting N-methyl-D-aspartate (NMDA) receptors, and its implications for autoimmune-driven neuropsychiatric manifestations. We identified 19 published case reports of NMDA receptor encephalitis associated with SARS-CoV-2 infection or vaccination by a systematic literature search. The significance of these reports was limited since it is not clear if a coincidental or causal relationship exists between SARS-CoV-2 infection or vaccination and manifestation of NMDA receptor encephalitis. The included studies were hampered by difficulties in establishing","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Mar","modification":"2025-04-22T01:02:34.186Z","creation":"2025-04-05T19:49:18.122Z"},"accession":"S-EPMC10923949","cross_references":{"pubmed":["38459000"],"doi":["10.1038/s41398-024-02831-0"]}}