{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["37"],"submitter":["Esnault V"],"pubmed_abstract":["Late opportunistic infections (OI) occurring beyond the first year after kidney transplantation (KT) are poorly described and not targeted by prophylactic strategies. We performed a ten-year retrospective monocentric cohort study describing epidemiology, risk factors and impact of late OI occurring 1 year after KT. We included clinically symptomatic OI requiring treatment besides BK virus nephropathy. Control groups included early OI occurring in the first year after KT, and KT recipients without OI since KT and alive with a functional allograft at 1 year. Among 1066 KT recipients, 185 (19.4%) presented a first episode of OI 21.0 (8.0-45.0) months after KT: 120 late OI (64.9%) and 65 early OI (35.1%). Late OI were mainly viral (<i>N</i> = 83, 69.2%), mostly herpes zoster (HZ) (<i>N</i> = 3"],"journal":["Transplant international : official journal of the European Society for Organ Transplantation"],"pagination":["12065"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10926380"],"repository":["biostudies-literature"],"pubmed_title":["Beyond the First Year: Epidemiology and Management of Late-Onset Opportunistic Infections After Kidney Transplantation."],"pmcid":["PMC10926380"],"pubmed_authors":["Peiffer B","Esnault V","Fourati S","Morel A","Melica G","Champy C","Attias P","Fihman V","Gallien S","Angebault C","Matignon M","Grimbert P","Hoisnard L"],"additional_accession":[]},"is_claimable":false,"name":"Beyond the First Year: Epidemiology and Management of Late-Onset Opportunistic Infections After Kidney Transplantation.","description":"Late opportunistic infections (OI) occurring beyond the first year after kidney transplantation (KT) are poorly described and not targeted by prophylactic strategies. We performed a ten-year retrospective monocentric cohort study describing epidemiology, risk factors and impact of late OI occurring 1 year after KT. We included clinically symptomatic OI requiring treatment besides BK virus nephropathy. Control groups included early OI occurring in the first year after KT, and KT recipients without OI since KT and alive with a functional allograft at 1 year. Among 1066 KT recipients, 185 (19.4%) presented a first episode of OI 21.0 (8.0-45.0) months after KT: 120 late OI (64.9%) and 65 early OI (35.1%). Late OI were mainly viral (<i>N</i> = 83, 69.2%), mostly herpes zoster (HZ) (<i>N</i> = 3","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024","modification":"2026-07-15T01:14:55.131Z","creation":"2025-04-04T21:31:18.293Z"},"accession":"S-EPMC10926380","cross_references":{"pubmed":["38468638"],"doi":["10.3389/ti.2024.12065"]}}