{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Verstraeten R"],"funding":["NHLBI NIH HHS"],"pagination":["e029637"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10926821"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["13(2)"],"pubmed_abstract":["<h4>Background</h4>HIV and antiretroviral therapy (ART) have been associated with increased cardiovascular disease (CVD) risk in high-income countries. The authors studied the longitudinal association between HIV and ART and nonlaboratory Framingham Risk Score (FRS) in a middle-income country.<h4>Methods and results</h4>This longitudinal analysis of the NCS (Ndlovu Cohort Study), South Africa used baseline to 36-month follow-up data. Demographics, HIV, ART status, and cardiometabolic measures were obtained. FRS was used as a CVD risk measure. Through linear mixed models, FRS trends over time and the association with HIV were studied. Analysis included 1136 participants, with 609 (54%) having HIV, and 495 (81%) taking ART. At baseline, 9.8% of participants had a high FRS. People living with"],"journal":["Journal of the American Heart Association"],"pubmed_title":["No Evidence for an Association of HIV and Antiviral Treatment With Changes in Framingham Cardiovascular Risk Score in the Ndlovu Cohort Study."],"pmcid":["PMC10926821"],"funding_grant_id":["UG3 HL156388"],"pubmed_authors":["Barth RE","Grobbee DE","Coutinho RA","Venter F","Boateng D","Klipstein-Grobusch K","Scheuermaier K","Deville W","Verstraeten R","Tempelman H","Vos-Seda AG"],"additional_accession":[]},"is_claimable":false,"name":"No Evidence for an Association of HIV and Antiviral Treatment With Changes in Framingham Cardiovascular Risk Score in the Ndlovu Cohort Study.","description":"<h4>Background</h4>HIV and antiretroviral therapy (ART) have been associated with increased cardiovascular disease (CVD) risk in high-income countries. The authors studied the longitudinal association between HIV and ART and nonlaboratory Framingham Risk Score (FRS) in a middle-income country.<h4>Methods and results</h4>This longitudinal analysis of the NCS (Ndlovu Cohort Study), South Africa used baseline to 36-month follow-up data. Demographics, HIV, ART status, and cardiometabolic measures were obtained. FRS was used as a CVD risk measure. Through linear mixed models, FRS trends over time and the association with HIV were studied. Analysis included 1136 participants, with 609 (54%) having HIV, and 495 (81%) taking ART. At baseline, 9.8% of participants had a high FRS. People living with","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Jan","modification":"2025-04-22T16:18:02.396Z","creation":"2024-12-04T09:27:17.376Z"},"accession":"S-EPMC10926821","cross_references":{"pubmed":["38214319"],"doi":["10.1161/JAHA.123.029637"]}}