{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["37(2)"],"submitter":["Margaris I"],"pubmed_abstract":["<h4>Background</h4>Spontaneous esophageal perforation traditionally mandates urgent surgical treatment. Lately, esophageal stents have been used to reduce the associated morbidity and mortality. The current systematic review aimed to assess the efficacy of stents as a primary treatment option in this scenario.<h4>Methods</h4>A systematic search was conducted in PubMed/MEDLINE, Scopus and the Cochrane Library for studies published in the English language between 2000 and 2023. We included observational studies reporting on the use of stents, alongside conservative measures and drainage procedures, in patients with spontaneous esophageal perforations. Primary outcomes were sealing rate (persistent leak occlusion) and failure rate (mortality or conversion to a major surgical operation). Secon"],"journal":["Annals of gastroenterology"],"pagination":["156-171"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10927622"],"repository":["biostudies-literature"],"pubmed_title":["Efficacy of esophageal stents as a primary therapeutic option in spontaneous esophageal perforations: a systematic review and meta-analysis of observational studies."],"pmcid":["PMC10927622"],"pubmed_authors":["Michalopoulos NV","Sidiropoulos TA","Theodorou D","Margaris I","Triantafyllou T","Sideris G","Arkadopoulos N"],"additional_accession":[]},"is_claimable":false,"name":"Efficacy of esophageal stents as a primary therapeutic option in spontaneous esophageal perforations: a systematic review and meta-analysis of observational studies.","description":"<h4>Background</h4>Spontaneous esophageal perforation traditionally mandates urgent surgical treatment. Lately, esophageal stents have been used to reduce the associated morbidity and mortality. The current systematic review aimed to assess the efficacy of stents as a primary treatment option in this scenario.<h4>Methods</h4>A systematic search was conducted in PubMed/MEDLINE, Scopus and the Cochrane Library for studies published in the English language between 2000 and 2023. We included observational studies reporting on the use of stents, alongside conservative measures and drainage procedures, in patients with spontaneous esophageal perforations. Primary outcomes were sealing rate (persistent leak occlusion) and failure rate (mortality or conversion to a major surgical operation). Secon","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Mar-Apr","modification":"2025-05-29T20:50:41.809Z","creation":"2024-11-07T11:33:05.966Z"},"accession":"S-EPMC10927622","cross_references":{"pubmed":["38481783"],"doi":["10.20524/aog.2024.0857"]}}