{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Liu Y"],"funding":["the Key Clinical Specialty Construction Project (Head & Neck Surgery) of Health Commission of Hunan Province (Xiangwei Finance〔2019〕NO.4), and the Natural Science Foundation of Changsha","the Natural Science Foundation of Hunan Province"],"pagination":["633-640"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10930411"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["48(5)"],"pubmed_abstract":["Objectives
Tongue squamous cell carcinoma (TSCC) is a common cancer in the oral and maxillofacial region, which seriously endangers people's life and health.Heterogeneous nuclear ribonucleoprotein A2/B1(hnRNP A2/B1) is an RNA-binding protein that regulates the expression of a variety of genes and participates in the occurrence and development of a variety of cancers. This study aims to investigate the role of hnRNP A2/B1 in TSCC progression.Methods
The differential expression of hnRNP A2/B1 in oral squamous cell carcinoma (OSCC) and normal oral mucosa cells and tissues was analyzed based on the gene expression profiles of GSE146483 and GSE85195 in the Gene Expression Omnibus (GEO) database. The correlation between hnRNP A2/B1 expression and disease-free survival of TSCC pat"],"journal":["Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences"],"pubmed_title":["Expression and effect of heterogeneous nuclear ribonucleoprotein A2/B1 in tongue squamous cell carcinoma."],"pmcid":["PMC10930411"],"funding_grant_id":["kq2208149","2020JJ5333"],"pubmed_authors":["Liu Y","Shen X"],"additional_accession":[]},"is_claimable":false,"name":"Expression and effect of heterogeneous nuclear ribonucleoprotein A2/B1 in tongue squamous cell carcinoma.","description":"Objectives
Tongue squamous cell carcinoma (TSCC) is a common cancer in the oral and maxillofacial region, which seriously endangers people's life and health.Heterogeneous nuclear ribonucleoprotein A2/B1(hnRNP A2/B1) is an RNA-binding protein that regulates the expression of a variety of genes and participates in the occurrence and development of a variety of cancers. This study aims to investigate the role of hnRNP A2/B1 in TSCC progression.Methods
The differential expression of hnRNP A2/B1 in oral squamous cell carcinoma (OSCC) and normal oral mucosa cells and tissues was analyzed based on the gene expression profiles of GSE146483 and GSE85195 in the Gene Expression Omnibus (GEO) database. The correlation between hnRNP A2/B1 expression and disease-free survival of TSCC pat","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 May","modification":"2025-04-05T07:20:57.317Z","creation":"2025-04-05T07:20:57.317Z"},"accession":"S-EPMC10930411","cross_references":{"pubmed":["37539565"],"doi":["10.11817/j.issn.1672-7347.2023.220316"]}}