biostudies-literatureUnknown13(5)Segneanu AENovel nanotechnology based on herbal products aspires to be a high-performing therapeutic platform. This study reports the development of an original engineering carrier system that jointly combines the pharmacological action of <i>Chelidonium majus</i> and AuNPs, with unique properties that ensure that the limitations imposed by low stability, toxicity, absorption, and targeted and prolonged release can be overcome. The metabolite profile of Romanian wild-grown <i>Chelidonium majus</i> contains a total of seventy-four phytochemicals belonging to eight secondary metabolite categories, including alkaloids, amino acids, phenolic acids, flavonoids, carotenoids, fatty acids, sterols, and miscellaneous others. In this study, various techniques (XRD, FTIR, SEM, DLS, and TG/DTG) were employed to Plants (Basel, Switzerland)734https://www.ebi.ac.uk/biostudies/studies/S-EPMC10934343biostudies-literatureRomanian Wild-Growing <i>Chelidonium majus</i>-An Emerging Approach to a Potential Antimicrobial Engineering Carrier System Based on AuNPs: In Vitro Investigation and Evaluation.PMC10934343Segneanu AEBoia ERBejenaru CBoia SDumitru ABuema GBejenaru LEVlase GVlase TCiocalteu MVfalseRomanian Wild-Growing <i>Chelidonium majus</i>-An Emerging Approach to a Potential Antimicrobial Engineering Carrier System Based on AuNPs: In Vitro Investigation and Evaluation.Novel nanotechnology based on herbal products aspires to be a high-performing therapeutic platform. This study reports the development of an original engineering carrier system that jointly combines the pharmacological action of <i>Chelidonium majus</i> and AuNPs, with unique properties that ensure that the limitations imposed by low stability, toxicity, absorption, and targeted and prolonged release can be overcome. The metabolite profile of Romanian wild-grown <i>Chelidonium majus</i> contains a total of seventy-four phytochemicals belonging to eight secondary metabolite categories, including alkaloids, amino acids, phenolic acids, flavonoids, carotenoids, fatty acids, sterols, and miscellaneous others. In this study, various techniques (XRD, FTIR, SEM, DLS, and TG/DTG) were employed to 2024-01-01T00:00:00Z2024 Mar2026-06-25T03:20:22.388Z2026-06-25T03:08:08.675ZS-EPMC109343433847558010.3390/plants13050734