{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["29(5)"],"submitter":["Bauder C"],"pubmed_abstract":["A convenient protocol for the synthesis of 25,26,27-tribenzoyl-28-[((<i>S</i>)-1-diphenylphos- phanyl-propan-2-yl)oxy]-calix[4]arene via stereospecific methylation on Evans' oxazolidinone moiety was reported. According to the <sup>13</sup>C NMR analysis of this phosphine, the calix[4]arene skeleton adopted a 1,3-alternate conformation. The latter conformation of the macrocycle and the (<i>S</i>)-chirality of the carbon atom bearing the methyl substituent were confirmed by a single-crystal X-ray diffraction study. After coordination of the phosphinated ligand to the dimeric [RuCl<sub>2</sub>(<i>p</i>-cymene)]<sub>2</sub> organometallic precursor, the resulting arene-ruthenium complex was tested in the asymmetric reduction of acetophenone and alcohol was obtained with modest enantiomeric excess."],"journal":["Molecules (Basel, Switzerland)"],"pagination":["1156"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC10934826"],"repository":["biostudies-literature"],"pubmed_title":["Optically Pure Calixarenyl Phosphine via Stereospecific Alkylation on Evans' Oxazolidinone Moiety."],"pmcid":["PMC10934826"],"pubmed_authors":["Semeril D","Bauder C"],"additional_accession":[]},"is_claimable":false,"name":"Optically Pure Calixarenyl Phosphine via Stereospecific Alkylation on Evans' Oxazolidinone Moiety.","description":"A convenient protocol for the synthesis of 25,26,27-tribenzoyl-28-[((<i>S</i>)-1-diphenylphos- phanyl-propan-2-yl)oxy]-calix[4]arene via stereospecific methylation on Evans' oxazolidinone moiety was reported. According to the <sup>13</sup>C NMR analysis of this phosphine, the calix[4]arene skeleton adopted a 1,3-alternate conformation. The latter conformation of the macrocycle and the (<i>S</i>)-chirality of the carbon atom bearing the methyl substituent were confirmed by a single-crystal X-ray diffraction study. After coordination of the phosphinated ligand to the dimeric [RuCl<sub>2</sub>(<i>p</i>-cymene)]<sub>2</sub> organometallic precursor, the resulting arene-ruthenium complex was tested in the asymmetric reduction of acetophenone and alcohol was obtained with modest enantiomeric excess.","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Mar","modification":"2026-06-26T03:26:01.193Z","creation":"2025-04-06T14:32:56.244Z"},"accession":"S-EPMC10934826","cross_references":{"pubmed":["38474667"],"doi":["10.3390/molecules29051156"]}}